Chemotherapy is treatment with drugs that kill cancer cells or stop them from dividing, usually given through a vein or as pills. Because the drugs travel through the bloodstream, chemotherapy can reach cancer throughout the body, not just one spot. It is often used for mesothelioma and other asbestos-related cancers, either alone or combined with surgery, radiation, or newer immunotherapy.
Origin
The term was coined in the early 20th century by the German scientist Paul Ehrlich, combining "chemo" (chemical) with "therapy" to describe treating disease with chemicals. Its use against cancer expanded after World War II, when mustard-gas research led to the first cancer chemotherapy drugs.
Significance in Asbestos Context
For mesothelioma patients, chemotherapy is often the backbone of treatment. The most established regimen combines a platinum drug (cisplatin or carboplatin) with pemetrexed, and many patients now also receive immunotherapy. Chemotherapy can shrink tumors, ease symptoms, and extend survival, though it rarely cures mesothelioma on its own. How the disease responds to chemotherapy, and the side effects a patient endures, become part of the medical record that documents how severe the illness is. For a claim, records of each cycle, the drugs used, and their costs help establish both the seriousness of the disease and the medical expenses being sought.
Example Sentence
After diagnosis, she began chemotherapy with cisplatin and pemetrexed, and her care team tracked each cycle to gauge how the tumor responded.
Related Terms
Pemetrexed, Cisplatin, Immunotherapy, Mesothelioma, Palliative Care, Radiation Therapy
Notes
- Keep records of every chemotherapy cycle, including the specific drugs, dates, and billing; these document both disease severity and medical costs for a claim.
- Ask whether your regimen includes immunotherapy, which is now combined with or used in place of chemotherapy for some mesothelioma patients.
- Ask about clinical trials; mesothelioma treatment is evolving, and trials may offer options beyond standard chemotherapy.
In the research library
1,713 studies in our medical research library mention Chemotherapy in the title or abstract. Among the most cited:
- Do patients with weight loss have a worse outcome when undergoing chemotherapy for lung cancers?P.J. Ross, S. Ashley, A. Norton, et al, 2004 · British Journal of Cancer · cited 342 times
- Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trialL. Calabrò, A. Morra, E. Fonsatti, et al, 2013 · The Lancet. Oncology · cited 277 times
- Pressurised intraperitoneal aerosol chemotherapy: rationale, evidence, and potential indicationsM. Alyami, M. Hübner, F. Grass, et al, 2019 · The Lancet. Oncology · cited 270 times
- A systematic review on the efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for diffuse malignancy peritoneal mesotheliomaT.D. Yan, L. Welch, D. Black, et al, 2007 · Annals of Oncology · cited 251 times
- A multicentre randomised phase III trial comparing pembrolizumab versus single-agent chemotherapy for advanced pre-treated malignant pleural mesothelioma: the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trialS. Popat, A. Curioni-Fontecedro, U. Dafni, et al, 2020 · Annals of Oncology · cited 229 times
The journals that publish most on it: Lung Cancer (67), Cancers (55), Frontiers in Oncology (46).
Category: Treatments & Therapies · All Lexicon terms A–Z
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