Erythema is redness of the skin caused by increased blood flow through small vessels near the surface. It is a clinical sign, not a disease, and can result from inflammation, infection, allergic reaction, radiation, heat, or drug effects.
Origin
The term comes from the Greek 'erythēma,' meaning a flush or redness, from 'erythros' (red). It has been used in formal medical writing since at least the 18th century to describe visibly reddened skin.
Significance in Asbestos Context
For patients with asbestos-related disease, erythema is most often encountered as a side effect of cancer treatment rather than as a direct effect of asbestos itself. Radiation therapy to the chest for mesothelioma or lung cancer commonly causes radiation dermatitis, which begins as erythema in the treatment field. Certain chemotherapy drugs (including pemetrexed, often used for mesothelioma) and immunotherapies can also cause rashes, hand-foot syndrome, or infusion-site erythema that your oncology team will want to grade and manage. Asbestos fibers themselves do not typically cause a skin disease, so unexplained skin redness should be evaluated for other causes rather than assumed to be 'from asbestos.'
Example Sentence
Two weeks into radiation for her pleural mesothelioma, the patient developed erythema along the treatment field, and her radiation oncologist prescribed a topical cream and adjusted her skin-care routine.
Related Terms
Radiation Dermatitis, Pemetrexed, Hand-Foot Syndrome, Immunotherapy, Pleural Mesothelioma
Notes
- If you develop skin redness during radiation or chemotherapy, report it to your oncology team promptly. Early grading (CTCAE scale) guides treatment and may affect whether your dose is modified.
- Photograph the affected area with the date visible; serial photos help your medical team track progression and document treatment-related side effects in your medical record.
- Ask your oncology nurse for a written skin-care plan (gentle cleansers, fragrance-free moisturizers, sun protection) before starting chest radiation rather than waiting for symptoms.
- Do not assume new skin redness is caused by asbestos exposure; ask your doctor to evaluate for drug reaction, infection, radiation effect, or unrelated dermatologic conditions.
In the research library
5 studies in our medical research library mention Erythema in the title or abstract. Among the most cited:
- Clinical safety and activity of pembrolizumab in patients with malignant pleural mesothelioma (KEYNOTE-028): preliminary results from a non-randomised, open-label, phase 1b trialE.W. Alley, J. Lopez, A. Santoro, et al, 2017 · The Lancet. Oncology · cited 392 times
- Prevention of malignant seeding at drain sites by hypofractionated radiotherapy in patients with pleural mesotheliomaP. Kara, I. Ugur, C. Misirlioglu, et al, 2010 · Asia-Pacific Journal of Clinical Oncology · cited 5 times
- Pemetrexed-Induced Pseudocellulitis: A Diagnostic ConundrumL.A. Horton, A.B. Lyons, M.C. Kwa, et al, 2024 · Curēus · cited 4 times
- A case of malignant peritoneal mesothelioma suggesting the utility of combining double-contrast radiography and endoscopy with computed tomography for diagnosisH. Saito, S. Hasuda, J. Nasu, et al, 2017 · Clinical Journal of Gastroenterology · cited 2 times
- Occupational ceramic fibres dermatitis in PolandM. Kieć-Swierczyńska, J. Wojtczak, 2000 · Occupational Medicine · cited 2 times
The journals that publish most on it: Asia-Pacific Journal of Clinical Oncology (1), The Lancet. Oncology (1), Curēus (1).
Category: Diseases & Conditions · All Lexicon terms A–Z
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