Metastasis is the process by which cancer cells break away from the original tumor and spread to other parts of the body, forming new tumors. The spread usually happens through the bloodstream or the lymphatic system. Once a cancer has metastasized, it's generally more advanced and harder to treat.
Origin
From the Greek metastasis, meaning "a change" or "a moving from one place to another." It entered medical usage in the nineteenth century to describe the transfer of disease from one organ to another that isn't directly connected to it.
Significance in Asbestos Context
In asbestos-related cancers such as mesothelioma and lung cancer, whether the disease has metastasized affects staging, treatment options, and prognosis. Mesothelioma tends to spread locally within the chest or abdomen before it reaches distant sites, but advanced cases can involve lymph nodes, the opposite lung, or distant organs. For a legal claim, medical records documenting the extent of spread help establish how severe the illness is and the damages involved, including pain, shortened life expectancy, and the cost of care.
Example Sentence
The oncologist explained that the metastasis to my lymph nodes moved my mesothelioma to a later stage and changed the treatment plan.
Related Terms
Mesothelioma, Staging, Lymph Nodes, Prognosis, Tumor, Lung Cancer
Notes
- Ask your oncologist how staging scans (CT, PET, or MRI) describe any spread, and request copies of the radiology reports.
- Documentation of metastasis and its effects supports damages for pain, disability, and shortened life expectancy.
- Keep a record of how the disease's spread affects daily functioning; it can matter for both medical care and a claim.
In the research library
483 studies in our medical research library mention Metastasis in the title or abstract. Among the most cited:
- Quality of life of patients with end-stage peritoneal metastasis treated with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)K. Odendahl, W. Solass, C. Demtröder, et al, 2015 · European Journal of Surgical Oncology · cited 103 times
- Laparoscopy is Safe and Accurate to Evaluate Peritoneal Surface Metastasis Prior to Cytoreductive SurgeryR.A. Marmor, K.J. Kelly, A.M. Lowy, et al, 2016 · Annals of Surgical Oncology · cited 59 times
- Unresectable peritoneal metastasis treated by pressurized intraperitoneal aerosol chemotherapy (PIPAC) leading to cytoreductive surgery and hyperthermic intraperitoneal chemotherapyM. Alyami, F. Mercier, M. Siebert, et al, 2021 · European Journal of Surgical Oncology · cited 58 times
- The impact of Aggrus/podoplanin on platelet aggregation and tumour metastasisN. Fujita, S. Takagi, 2012 · Journal of Biochemistry · cited 50 times
- Giant solitary fibrous tumor of the liver with metastasis to the skeletal system successfully treated with trisegmentectomyS. Yilmaz, V. Kirimlioglu, E. Ertas, et al, 2000 · Digestive Diseases and Sciences · cited 49 times
The journals that publish most on it: PloS One (11), Frontiers in Oncology (10), Cancers (10).
Category: Biological & Molecular Mechanisms · All Lexicon terms A–Z
This page is provided for general informational purposes and does not constitute legal advice. Every asbestos case turns on its own facts, exposure history, diagnosis, deadlines, available evidence, and applicable law. Reviewing this page does not create an attorney-client relationship. For advice about your specific situation, call 833-4-ASBESTOS for a free case review.