Pleurisy is inflammation of the pleura, the two-layered membrane that wraps the lungs and lines the inside of the chest wall. When the layers become inflamed, they rub against each other with each breath, causing sharp, stabbing chest pain that worsens with breathing, coughing, or movement. Pleurisy is a symptom or condition, not a disease in itself, and it has many possible causes.
Origin
From the Greek pleuritis, meaning "inflammation of the side," derived from pleura (rib, side). The condition has been described in medical writings since Hippocrates, who used the term to describe painful breathing accompanied by fever.
Significance in Asbestos Context
In someone with a history of asbestos exposure, pleurisy is often the body's response to asbestos-related changes in the pleura, including benign asbestos pleural effusion (often the earliest asbestos-related condition to appear, sometimes within 10 years of exposure), pleural plaques, diffuse pleural thickening, or pleural mesothelioma. Recurrent or unexplained pleurisy in an exposed person should prompt imaging (chest CT) and specialist evaluation to rule out mesothelioma, because pleural pain can be the first sign of malignancy before a mass is visible. Documentation of pleurisy episodes in medical records (including dates, imaging, and fluid analyses) can be important evidence of when asbestos-related disease first appeared, which may affect the timing of a legal claim.
Example Sentence
When the patient described recurring sharp chest pain that worsened with deep breaths, his pulmonologist ordered a CT scan because pleurisy in a former insulator with known asbestos exposure can be an early warning of mesothelioma.
Related Terms
Pleura, Pleural Effusion, Pleural Plaque, Diffuse Pleural Thickening, Benign Asbestos Pleural Effusion, Mesothelioma
Notes
- If you have a known asbestos exposure history and develop pleuritic chest pain, ask your doctor for a chest CT scan rather than only a chest X-ray. CT is far more sensitive for detecting pleural plaques, effusions, and early mesothelioma.
- If fluid is drained from around your lung (thoracentesis), ask that the fluid be sent for cytology, and request that any biopsy tissue be preserved; these samples can be critical for diagnosis and for any future legal claim.
- Keep copies of all imaging reports, pulmonology notes, and discharge summaries documenting pleurisy episodes. The date pleural disease first appeared can affect statute of limitations deadlines in asbestos cases.
- Benign asbestos pleural effusion is a recognized diagnosis but is a diagnosis of exclusion, meaning mesothelioma and other cancers must be ruled out first; do not accept a benign label without thorough workup.
In the research library
56 studies in our medical research library mention Pleurisy in the title or abstract. Among the most cited:
- An outbreak of pleural mesothelioma and chronic fibrosing pleurisy in the village of Karain/Urgüp in AnatoliaY.I. Baris, A.A. Sahin, M. Ozesmi, et al, 1978 · Thorax · cited 173 times
- Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbitsA.M. Boylan, C. Rüegg, K.J. Kim, et al, 1992 · The Journal of Clinical Investigation · cited 74 times
- Respiratory function changes after asbestos pleurisyP.H. Wright, A. Hanson, L. Kreel, et al, 1980 · Thorax · cited 69 times
- Ventilatory failure due to asbestos pleurisyA. Miller, A.S. Teirstein, I.J. Selikoff, 1983 · The American Journal of Medicine · cited 68 times
- Pathogenesis of pleurisy, pleural fibrosis, and mesothelial proliferationA. Herbert, 1986 · Thorax · cited 59 times
The journals that publish most on it: Thorax (9), Respirology (3), Lung Cancer (3).
Category: Diseases & Conditions · All Lexicon terms A–Z
This page is provided for general informational purposes and does not constitute legal advice. Every asbestos case turns on its own facts, exposure history, diagnosis, deadlines, available evidence, and applicable law. Reviewing this page does not create an attorney-client relationship. For advice about your specific situation, call 833-4-ASBESTOS for a free case review.