Pleurodesis is a procedure that seals the space between the lung and the chest wall to stop fluid from building up there again. A doctor introduces a substance, often sterile talc, that inflames the two surfaces so they stick together, closing the gap where fluid collects. It's a common palliative treatment for the recurrent pleural effusions that trouble many mesothelioma patients.
Origin
From the Greek pleura, meaning "rib" or "side," and desis, "a binding together." Talc pleurodesis was developed over the twentieth century as a way to manage repeated fluid buildup in the chest without leaving a drain in place permanently.
Significance in Asbestos Context
Many people with pleural mesothelioma develop pleural effusions, fluid that gathers around the lung and causes breathlessness, and pleurodesis is one of the main ways to relieve it. By fusing the pleural surfaces, the procedure keeps fluid from re-accumulating, easing breathing and reducing the need for repeated drainage. It doesn't treat the cancer itself, so it's used to improve comfort and quality of life. Because it addresses symptoms that seriously affect daily living, the burden of recurrent effusions and treatments like pleurodesis is relevant when documenting how the disease has affected a patient.
Example Sentence
After his third fluid drainage in two months, his doctor recommended pleurodesis to keep the effusion from returning and to ease his breathing.
Related Terms
Pleural Effusion, Pleural Mesothelioma, Thoracentesis, Indwelling Pleural Catheter, Palliative Care, Dyspnea
Notes
- Ask your care team whether talc pleurodesis or an indwelling pleural catheter is better for your situation; both manage recurrent fluid differently.
- Keep records of every effusion, drainage, and pleurodesis procedure, as this documents the disease's impact for both medical and legal purposes.
- Ask what to expect during recovery, including chest discomfort and a short hospital stay, so you can plan for support at home.
In the research library
99 studies in our medical research library mention Pleurodesis in the title or abstract. Among the most cited:
- Mechanisms of pleurodesisF. Rodriguez-Panadero, A. Montes-Worboys, 2012 · Respiration; International Review of Thoracic Diseases · cited 93 times
- Talc slurry pleurodesis. Pleural fluid and histologic analysisL. Kennedy, R.A. Harley, S.A. Sahn, et al, 1995 · Chest · cited 88 times
- Tumor type influences the effectiveness of pleurodesis in malignant effusionsS. Bielsa, P. Hernández, F. Rodriguez-Panadero, et al, 2011 · Lung · cited 46 times
- Pleurodesis outcome in malignant pleural mesotheliomaE.T. Fysh, S.K. Tan, C.A. Read, et al, 2013 · Thorax · cited 37 times
- A randomized controlled trial of the efficacy of cosmetic talc compared with iodopovidone for chemical pleurodesisR. Agarwal, A.S. Paul, A.N. Aggarwal, et al, 2011 · Respirology · cited 34 times
The journals that publish most on it: Chest (8), Respirology (7), Respiration; International Review of Thoracic Diseases (5).
Category: Treatments & Therapies · All Lexicon terms A–Z
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