Sputum is the thick mucus produced deep in the lungs and airways that is brought up by coughing. It is different from saliva or spit, which comes from the mouth. Doctors examine sputum to look for infection, cancer cells, blood, and sometimes asbestos bodies or fibers.
Origin
From the Latin sputum, meaning "that which is spit," derived from the verb spuere, "to spit." The word has appeared in medical writing since classical antiquity and remains the standard clinical term for material coughed up from the lower airways.
Significance in Asbestos Context
For someone with a history of asbestos exposure, a sputum sample can sometimes show asbestos bodies (also called ferruginous bodies), coated fibers that confirm prior inhalation of asbestos. Sputum cytology may also detect abnormal or cancerous cells in patients being evaluated for lung cancer, though it is far less sensitive than imaging or biopsy and a negative result does not rule disease out. In a legal claim, a sputum report that documents asbestos bodies can become part of the exposure evidence in the medical record, while sputum cytology findings may support a lung cancer diagnosis that is later confirmed by biopsy.
Example Sentence
After her chest CT showed a suspicious nodule, the pulmonologist ordered sputum cytology and a follow-up bronchoscopy to evaluate whether the mass was malignant.
Related Terms
Asbestos Bodies, Ferruginous Bodies, Bronchoscopy, Cytology, Bronchoalveolar Lavage, Lung Cancer
Notes
- Collect samples first thing in the morning, before eating or brushing teeth, and cough deeply from the chest rather than clearing the throat. Shallow samples are often rejected as inadequate.
- Ask whether the lab is looking specifically for asbestos bodies, malignant cells, infection, or all three; the staining and processing differ, and you want the right test ordered.
- A negative sputum result does not rule out asbestos exposure or lung cancer; if suspicion remains, push for CT imaging, bronchoscopy, or biopsy.
- Keep copies of all pathology and cytology reports. Language such as "ferruginous bodies identified" or "atypical cells" can become important documentation in both treatment decisions and any future legal claim.
In the research library
69 studies in our medical research library mention Sputum in the title or abstract. Among the most cited:
- A method for extracting ferruginous bodies from sputum and pulmonary tissueM.J. Smith, B. Naylor, 1972 · American Journal of Clinical Pathology · cited 141 times
- A procedure for the isolation of amosite asbestos and ferruginous bodies from lung tissue and sputumM.G. Williams, R.F. Dodson, C. Corn, et al, 1982 · Journal of Toxicology and Environmental Health · cited 66 times
- Assessment of hazardous dust exposure by BAL and induced sputumE. Fireman, J. Greif, Y. Schwarz, et al, 1999 · Chest · cited 52 times
- Relevance of asbestos bodies in sputumH. Teschler, A.B. Thompson, R. Dollenkamp, et al, 1996 · The European Respiratory Journal · cited 34 times
- Comparison of sputum and lung asbestos body counts in former asbestos workersV.L. Roggli, S.D. Greenberg, J.W. McLarty, et al, 1980 · The American Review of Respiratory Disease · cited 33 times
The journals that publish most on it: American Journal of Industrial Medicine (5), British Journal of Industrial Medicine (5), The European Respiratory Journal (4).
Category: Diagnostic Tools & Biomarkers · All Lexicon terms A–Z
This page is provided for general informational purposes and does not constitute legal advice. Every asbestos case turns on its own facts, exposure history, diagnosis, deadlines, available evidence, and applicable law. Reviewing this page does not create an attorney-client relationship. For advice about your specific situation, call 833-4-ASBESTOS for a free case review.