Corrigendum: Why Be One Protein When You Can Affect Many? The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma

Our plain-English summary of Corrigendum: Why Be One Protein When You Can Affect Many? The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma, by T.G. Johnson, K. Schelch, S. Mehta, et al (Frontiers in Cell and Developmental Biology, 2019).

The study

• Authors: T.G. Johnson, K. Schelch, S. Mehta, A. Burgess, G. Reid
• Journal: Frontiers in Cell and Developmental Biology
• Published: 2019;7:293
• Cited by: 2 articles, as counted by NIH iCite
• Read it: PubMed · Publisher · Free full text

Abstract

[This corrects the article doi:10.3389/fcell.2019.00221.].

Copyright © 2019 Johnson, Schelch, Mehta, Burgess and Reid.

In plain English

This document is a correction notice (a corrigendum), not a research study. It corrects an earlier 2019 article by the same authors in the same journal, titled "Why Be One Protein When You Can Affect Many? The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma." YB-1 (Y-box binding protein-1) is a protein. The notice stated that the original article contained one wording error: the authors had written "adenylation" where they meant "acetylation." The error was in a paragraph about YB-1 being released from cells under stress. The corrected text says that two lysine residues, numbered 301 and 304, are the site of acetylation in hemodialysis patients. That paragraph describes earlier studies by other research groups, and this notice reports no new data of its own. It does not study asbestos exposure, workers, or people with mesothelioma. The authors apologized for the error. They stated that it does not change the scientific conclusions of the original article in any way, and that the original article has been updated.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: correction notice (corrigendum) to an earlier article; not a study
• Main results:
  • The original article mistakenly used the word "adenylation" instead of "acetylation".
  • The correction is in the section "YB-1: a malignant jack of all trades", in the subsection on YB-1 being secreted into the extracellular space under cellular stress, paragraph two.
  • The corrected sentence refers to two lysine residues (numbered 301 and 304) as the site of acetylation in hemodialysis patients. This describes earlier work by other researchers, which the original article cited.
• The authors' conclusion: The authors apologized for the error and stated that it does not change the scientific conclusions of the original article in any way. They said the original article has been updated.

Topics

Medical terms in this study, explained in our Lexicon: Lung Cancer, Mesothelioma.

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