Intra-abdominal benign multicystic peritoneal mesothelioma

Our plain-English summary of Intra-abdominal benign multicystic peritoneal mesothelioma, by I. Jouvin, A. Dohan, P. Gergi, et al (Journal of Visceral Surgery, 2014).

The study

• Authors: I. Jouvin, A. Dohan, P. Gergi, M. Pocard
• Journal: Journal of Visceral Surgery
• Published: 2014;151(2):155-7
• Type of article: Case report
• Cited by: 16 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

Abstract

Benign multicystic peritoneal mesotheliomas are rare: pre-operative diagnosis relies on proper imaging. The differential diagnosis includes pseudomyxoma peritonei and other peritoneal cysts. Absence of previous surgical resection offers the best chance of success when complete resection is performed in a specialized center. We report the case of a 43 year-old man with benign multicystic peritoneal mesothelioma treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Copyright © 2013 Elsevier Masson SAS. All rights reserved.

In plain English

This short case report, published as a 'surgical images' article, described one 43-year-old man without symptoms who was referred to a Paris surgical unit after cysts in the lining of the abdomen were found by chance. MRI showed a lesion with many compartments; CT showed fluid but not the internal dividing walls. Before surgery, normal tumor markers and the appearance of the liver edges led the team to favor pseudomyxoma peritonei over mesothelioma. A multidisciplinary meeting recommended surgery plus heated chemotherapy inside the abdomen (HIPEC), and a French national network for rare peritoneal cancers gave a second opinion. During the operation, many clear cystic nodules were found, leading to a diagnosis of benign multicystic peritoneal mesothelioma. Surgeons removed the abdominal lining, the omentum and lymph nodes, then gave HIPEC with oxaliplatin; pathology confirmed the diagnosis. The article did not mention asbestos and reported no follow-up. The authors stated that the best chance of success comes when there has been no previous surgical resection and complete resection is performed in a specialized center.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report (short 'surgical images' article)
• Who was studied: One asymptomatic 43-year-old man referred to a digestive and cancer surgery unit at Lariboisière hospital, Paris, France, for peritoneal cysts discovered by chance
• Main results:
  • MRI showed a multiloculated lesion with dense contents. CT showed fluid density but could not show the multiple septa (internal dividing walls).
  • Before surgery, normal tumor markers and peri-hepatic scalloping (scalloped liver edges) led the team to favor pseudomyxoma peritonei.
  • During the operation, multiple translucent cystic nodules were found. This led to a diagnosis of benign multicystic peritoneal mesothelioma and ruled out pseudomyxoma peritonei.
  • Complete excision consisted of total peritonectomy including the Douglas pouch, omentectomy and hepatic pedicle lymphadenectomy. It was followed by HIPEC with oxaliplatin (460 mg/m2). Pathology confirmed the diagnosis.
• The authors' conclusion: The authors stated that the absence of previous surgical resection offers the best chance of success when complete resection is performed in a specialized center.

Topics

The National Library of Medicine indexes this study under subjects our site covers: Mesothelioma, Peritoneal mesothelioma.

Medical terms in this study, explained in our Lexicon: Peritoneal Mesothelioma, Differential Diagnosis, Surgical Resection, Cytoreductive Surgery, HIPEC.

Related studies

• Benign multicystic peritoneal mesothelioma: a rare cause of intra-abdominal cystic disease — B. Campbell, D. Mehanna, et al. (2017)
• Benign multicystic mesothelioma and peritoneal inclusion cysts: are they the same clinical and histopathological entities? A systematic review to find an evidence-based management — A.M.C. Rapisarda, A. Cianci, et al. (2018)
• Multi-institutional experience of diffuse intra-abdominal multicystic peritoneal mesothelioma — T.C. Chua, T.D. Yan, et al. (2011)
• Benign multicystic peritoneal mesothelioma presenting as a ghost abdominal mass — H. Jerraya, W. Ghariani, et al. (2016)
• A Case of Abdominal Discomfort Caused by Benign Multicystic Peritoneal Mesothelioma — T.G. Cotter, J.S. Van Arnam, et al. (2016)
• Cytomorphologic characteristics of fine needle core biopsy of multicystic peritoneal mesothelioma: a case report and review of the literature — A.M. Kemp, R. Nayar, et al. (2010)

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