Sarcomatous mesothelioma in the left ventricle: a rare entity

Our plain-English summary of Sarcomatous mesothelioma in the left ventricle: a rare entity, by M. Jianyang, Z. Xiuhui, Y. Hongsheng, et al (The Journal of Thoracic and Cardiovascular Surgery, 2001).

The study

• Authors: M. Jianyang, Z. Xiuhui, Y. Hongsheng, D. Li, Z. Huaibin, S. Yingkang
• Journal: The Journal of Thoracic and Cardiovascular Surgery
• Published: 2001;122(2):394-5
• Type of article: Case report
• Cited by: 2 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

In plain English

This article was a case report from West China Hospital, Sichuan University. A 51-year-old man was admitted to hospital with breathlessness on exertion and palpitations that had increased over the previous 6 months. He had no history of exposure to asbestos. Heart ultrasound (echocardiography) showed a 9.0 by 3.0 cm mobile mass inside the left ventricle. It was attached to the ventricular septum, the wall between the heart's two lower chambers, and there was significant leakage of the mitral valve. Surgeons removed the tumor through an opening in the left ventricle. It measured 10 by 3 by 4 cm and reached the opening of the mitral valve without damaging the valve. Microscopic and immunohistochemical tests confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1. The patient recovered without complications and left hospital on the ninth day after surgery. At 3 months, echocardiography showed no remaining mass, and he was doing well at 4 months. The authors described mesotheliomas arising from the left ventricle as rare. Because it describes one person, the report does not show how often such tumors occur.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report (single patient treated by surgical resection)
• Who was studied: one 51-year-old man treated at West China Hospital, Sichuan University, Chengdu, People's Republic of China, with exertional dyspnea and palpitations increasing over 6 months
• Exposure: The article states the patient had no history of asbestos exposure; no fiber type or job is described
• Main results:
  • Echocardiography showed a 9.0 by 3.0 cm mobile mass within the left ventricle, attached to the ventricular septum
  • Significant mitral regurgitation was seen before surgery
  • At surgery the tumor measured 10 by 3 by 4 cm and reached the mitral valve orifice, but the valve was not damaged
  • Microscopic and immunohistochemical examination of the removed specimen confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1
  • The patient was discharged on the ninth postoperative day
  • At 3 months, echocardiography showed a normal mitral valve and no residual mass, and the patient was doing well at 4 months
• The authors' conclusion: The authors stated that, to their knowledge, mesotheliomas originating from the left ventricle are rare, and described primary sarcomatous mesothelioma arising there as extremely uncommon

Topics

The National Library of Medicine indexes this study under subjects our site covers: Mesothelioma.

Medical terms in this study, explained in our Lexicon: Mesothelioma.

Related studies

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• Sarcomatous pleural mesothelioma metastatic to left ventricular endocardium — N. Senkottaiyan, L.M. Seacord, et al. (2006)
• Case report and analysis of the literature on sarcomatous mesothelioma of the left atrium — W. Rouabeh, T. Cherif, et al. (2023)
• Benign mesothelial proliferation with effusion. Clinicopathologic entity that may mimic malignancy — R.M. Hansen, J.G. Caya, et al. (1984)
• Pericardial mesothelioma presenting as left atrial thrombus in a patient with mitral stenosis — Y. Miyamoto, S. Nakano, et al. (1996)
• Rare cause of myocardial infarction, stroke, and lung tumour — M. Medvegy, A. Szekula, et al. (2013)

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