Villous tumors of the stomach and duodenum; report of three cases

Our plain-English summary of Villous tumors of the stomach and duodenum; report of three cases, by A.D. Meltzer, B.I. Ostrum, H.J. Isard (Radiology, 1966).

The study

• Authors: A.D. Meltzer, B.I. Ostrum, H.J. Isard
• Journal: Radiology
• Published: 1966;87(3):511-3
• Type of article: Case report
• Cited by: 46 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

In plain English

This 1966 article from the Division of Radiology at Albert Einstein Medical Center, Philadelphia, described three patients with villous tumors, two in the duodenum and one in the stomach. The article does not mention asbestos. In the first patient, a 59-year-old man, the final pathology was recurrent low-grade villous adenocarcinoma of the duodenum. In the second, a 60-year-old man, it was villous adenoma of the periampullary duodenal mucosa with areas of microinvasion. In the third, a 72-year-old woman, it was multiple, partly villous adenomata of the stomach with malignant transformation, and there was metastatic carcinoma to the regional lymph nodes. On barium X-ray, contrast material caught among the tumors' projections produced what the authors called a "soap-bubble" or frond-like appearance. Counting these three cases and earlier published reports, the authors stated that 5 of 6 reported cases outside the colon showed carcinomatous properties. The authors concluded that this X-ray appearance suggests the diagnosis, that the high rate of malignancy parallels that of colon villous tumors, and that the term "villous tumor" is preferable to "villous adenoma."

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report (three cases), with a brief literature review
• Who was studied: Three patients at Albert Einstein Medical Center, Philadelphia: a 59-year-old Negro male and a 60-year-old Negro male (in the article's terms), both with duodenal tumors, and a 72-year-old white woman with stomach tumors
• Main results:
  • Case I (59-year-old man): the final pathology was recurrent low-grade villous adenocarcinoma of the duodenum
  • Case II (60-year-old man): the final pathology was villous adenoma of the periampullary duodenal mucosa with areas of microinvasion
  • Case III (72-year-old woman): the final pathology was multiple, partly villous adenomata of the stomach with malignant transformation and invasion of the submucosa, with metastatic carcinoma to the regional lymph nodes
  • On barium X-ray, retained contrast among the villous projections produced a soap-bubble or frond-like appearance
  • Counting their own three cases and earlier reports, the authors stated that 5 of a total of 6 reported cases outside the colon showed carcinomatous properties
• The authors' conclusion: The authors concluded that the characteristic soap-bubble X-ray appearance suggests the diagnosis, that the high incidence of malignancy parallels the behavior of colonic villous tumors, and that the term "villous tumor" is preferred over "villous adenoma."

Topics

The National Library of Medicine indexes this study under subjects our site covers: Mesothelioma, Stomach cancer.

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