7 results for “Reaction Department”
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Medical study · Medical research · 1983
Acute lung response to amosite asbestos: a morphological study
This was an animal experiment in guinea pigs. It examined the lung's reaction during the week after amosite asbestos was placed in the windpipe. Exposed animals received 17.5 mg of ground commercial-grade amosite…
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Medical study · Medical research · 1994
Iron associated with asbestos bodies is responsible for the formation of single strand breaks in phi X174 RFI DNA
…iron was responsible. Amosite fibres (5000 fibres/reaction), with a similar length distribution to that of the asbestos bodies, did not catalyse detectable amounts of single strand breaks in DNA under identical reaction conditions. The results…
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Medical study · Medical research · 1983
Method for removing the ferruginous coating from asbestos bodies
…treatment consisted of an 8% oxalic acid bath used at various temperatures. It was determined that at 75 degrees C the reaction resulted in removal of the ferruginous coat, leaving an exposed core for further analysis…
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Medical study · Medical research · 1988
Asbestos-induced endothelial cell activation and injury. Demonstration of fiber phagocytosis and oxidant-dependent toxicity
…iron present within amosite asbestos fibers by deferoxamine produced a 33% reduction in asbestos cytotoxicity, suggesting a potential role for hydroxyl radical-mediated injury via the iron-catalyzed Haber-Weiss reaction.(ABSTRACT TRUNCATED AT 250 WORDS)
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Medical study · Medical research · 2011
Morphological and chemical mechanisms of elongated mineral particle toxicities
…may cause disease. They discussed how particle size affects lung clearance and movement elsewhere, how surface area relates to reactions with cells, and iron chemistry in several minerals. Reviewed findings included that asbestos fibers can generate…
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Medical study · Medical research · 1997
Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos
…in the same level of intracellular GSH depletion and efflux and the same decrease in gamma-GCS activity as treatment with unmodified crocidolite, which suggests that iron-catalyzed reactions were not responsible for the GSH depletion.
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Medical study · Medical research · 1997
Mobilization of iron from urban particulates leads to generation of reactive oxygen species in vitro and induction of ferritin synthesis in human lung epithelial cells
…Urban air particulates also contain iron, and some of the pathological effects after inhalation may be due to reactive oxygen species produced by iron-catalyzed reactions. Two standard reference material (SRM) urban air particulate samples were…