3 results for “Reaction Department”
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Medical study · Medical research · 1992
The role of free radicals in asbestos-induced diseases
…this reactive radical. However, asbestos also appears to catalyze electron transfer reactions that do not require iron. Iron chelators either inhibit or augment asbestos-catalyzed generation of the hydroxyl radical and/or pathological changes, depending on…
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Medical study · Medical research · 2003
Cell signaling and transcription factor activation by asbestos in lung injury and disease
…through receptor-mediated events or integrins. Alternatively, they may be stimulated by oxidants generated both during phagocytosis of minerals and/or by redox reactions on the mineral surface. Once initiated, these pathways can lead to promotion…
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Medical study · Medical research · 1992
NHLBI workshop summary. Environmental lung diseases. Relationship between acute inflammatory responses to air pollutants and chronic lung disease
…included microdosimetry of inhaled gases and particles, the transfer of ozone and nitrogen dioxide across the air-tissue interface, oxidative reactions involving nitric oxide, early events leading to lung fibrosis, chronic injury in the proximal alveolar…