3 results for “Reaction Department”
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Medical study · Medical research · 2021
UHRF1 Is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma
…in malignant pleural mesothelioma (MPM). This study was undertaken to explore the therapeutic potential of targeting UHRF1 in MPM. Microarray, real-time quantitative reverse transcription-polymerase chain reaction, immunoblot, and immunohistochemistry techniques were used to evaluate…
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Medical study · Medical research · 2000
Crocidolite induces cell transformation and p53 gene mutation in BALB/c-3T3 cells
…foci and subjected to mutational analysis. Eleven exons of the p53 gene from eight transformed cell lines were analyzed for alterations using polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP). Alterations were found in seven…
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Medical study · Medical research · 2013
miR-1 induces growth arrest and apoptosis in malignant mesothelioma
…comparators. To confirm microarray data, we used real-time quantitative polymerase chain reaction. Representative cell lines H513 and H2052 were used in functional analyses of miR-1. In addition to several novel MPM-associated microRNAs, we…