5 results for “Reaction Department”
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Medical study · Medical research · 2016
Effects of Chrysotile Exposure in Human Bronchial Epithelial Cells: Insights into the Pathogenic Mechanisms of Asbestos-Related Diseases
…glycogen synthase kinase-3β (GSK-3β), and Akt were performed to confirm their involvement in asbestos-induced EMT. Real-time polymerase chain reaction (PCR), Western blotting, and gelatin zymography were performed to detect mRNA…
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Medical study · Medical research · 2005
Potential toxicity of nonregulated asbestiform minerals: balangeroite from the western Alps. Part 3: Depletion of antioxidant defenses
…crocidolite incubation. This effect was not related to any increased content of oxidized glutathione, or to any enhanced efflux of glutathione, suggesting that balangeroite fibers, like crocidolite, might favor the reaction of GSH with other molecules.
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Medical study · Medical research · 2013
Asbestos-like pathogenicity of long carbon nanotubes alleviated by chemical functionalization
This was a short-term experiment in mice testing whether chemically modifying long multi-walled carbon nanotubes changes the asbestos-like reactions they cause. The authors took long, unmodified nanotubes previously used by another research group…
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Medical study · Medical research · 2012
Surface reactivity and cell responses to chrysotile asbestos nanofibers
…Alps. Electron microscopy, X-ray diffraction, and fluorescence spectroscopy revealed that the procedure does not affect mineralogical and chemical composition. Surface reactions related to oxidative stress, free radical generation, bioavailability of iron, and antioxidant depletion, revealed…
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Medical study · Medical research · 2003
Long and short fiber amosite asbestos alters at a different extent the redox metabolism in human lung epithelial cells
…cells A549, long amosite fibers, more effectively than the short ones, initiate free radical reactions, inhibit the glucose 6-phosphate dehydrogenase activity and the pentose phosphate pathway, decrease the intracellular level of reduced glutathione, and increase…