20 results for “General Electric”
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Medical study · Medical research · 1992
Performance of two general job-exposure matrices in a study of lung cancer morbidity in the Zutphen cohort
…of lung cancer morbidity incidence. The two general job-exposure matrices generally disagreed with regard to exposure classification because of differences in exposure assessment and level of detail of the job axis. When compared with self…
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Medical study · Medical research · 2024
The asbestos-asbestosis exposure-response relationship: a cohort study of the general working population
…observed increasing risk with increasing cumulative exposure in the inception population. This study found exposure-response relations between cumulative asbestos exposure and incident asbestosis in the Danish general working population with mainly low-level exposed occupations…
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Medical study · Medical research · 2012
Impact of occupational carcinogens on lung cancer risk in a general population
…highly exposed industrial cohorts. Our aim was to quantify lung cancer burden attributable to occupational carcinogens in a general population. We applied a new job-exposure matrix (JEM) to translate lifetime work histories, collected by personal…
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Medical study · Medical research · 2006
Polymorphisms in DNA repair genes as risk factors for asbestos-related malignant mesothelioma in a general population study
This population-based case-control study asked whether inherited variants in four DNA repair genes (XRCC1, XRCC3, XPD and OGG1) were linked to malignant mesothelioma of the pleura. It was set in Casale Monferrato, Italy, where an asbestos cement…
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Medical study · Medical research · 2019
Peritoneal mesothelioma and asbestos exposure: a population-based case-control study in Lombardy, Italy
…to its rarity, PeM has rarely been investigated in community-based studies. We examined the association between asbestos exposure and PeM risk in a general population in Lombardy, Italy. From the regional mesothelioma registry, we selected…
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Medical study · Medical research · 2013
A genome-wide association study for malignant mesothelioma risk
This genome-wide association study looked for inherited DNA variants (SNPs) linked to malignant mesothelioma risk. The authors compared 428 mesothelioma patients from Western Australia and Queensland with 1269 general-population controls from Busselton, Western Australia…
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Medical study · Medical research · 2020
Re Ferrante et al (2020). Mortality and mesothelioma incidence among chrysotile asbestos miners in Balangero, Italy: A cohort study
…incomplete, explanation. Lung cancer SMRs versus the general population were almost identical: 1.14 (95% CI 0.81 to 1.55) and 1.16 (0.87 to 1.52). By cumulative exposure (fiber/mL-years), Pira…
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Medical study · Medical research · 2017
Germline mutations in DNA repair genes predispose asbestos-exposed patients to malignant pleural mesothelioma
…lifetime asbestos exposure had been estimated from interviews about exposure at work, at home and in the general environment. The authors sequenced 94 cancer-related genes from blood samples and compared the results with 96 Italian…
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Medical study · Medical research · 2019
Gender differences in pleural mesothelioma occurrence in Lombardy and Piedmont, Italy
…exposure in men translated into a 7 to 10 year advancement in mesothelioma occurrence. They noted that exposure information was not available for the general population, so rates by actual asbestos exposure could not be calculated.
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Medical study · Medical research · 2011
Comparison of exposure assessment methods for occupational carcinogens in a multi-centre lung cancer case-control study
…re-applied to all study subjects. Third, an independent general population JEM (GPJEM) was created by occupational exposure experts not involved in the original study, and applied to study subjects. Results from these methods were compared…
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Medical study · Medical research · 2014
Parental occupational exposure and risk of childhood central nervous system tumors: a pooled analysis of case-control studies from Germany, France, and the UK
…face-to-face or by telephone. A general population job-exposure matrix was used to assign a level of exposure to each job. Logistic regression models were fitted to compute odds ratios and 95 % confidence intervals…
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Medical study · Medical research · 2003
Estimating exposures in the asphalt industry for an international epidemiological cohort study of cancer risk
…companies enrolled in the cohort, plus the Swedish asphalt paving industry in general. Most companies were engaged in road paving and asphalt mixing, but some also participated in general construction and roofing. Coal tar use was…
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Medical study · Medical research · 2010
A case-control study of lung cancer nested in a cohort of European asphalt workers
…risk. A sizable proportion of the excess mortality from lung cancer relative to the general population observed in the earlier cohort phase is likely attributable to high tobacco consumption and possibly to coal tar exposure, whereas…
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Medical study · Medical research · 2017
Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies
…asbestos exposure and assessed the joint effect of asbestos exposure and smoking by sex and lung cancer subtype in general population studies. We pooled 14 case-control studies conducted in 1985-2010 in Europe and Canada…
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Medical study · Medical research · 2016
Pleural mesothelioma and occupational and non-occupational asbestos exposure: a case-control study with quantitative risk assessment
…Monferrato (north west Italy) is an area with an exceptionally high incidence of mesothelioma caused by asbestos contamination at work and in the general environment from the asbestos-cement Eternit plant that was operational until 1986…
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Medical study · Medical research · 2012
Hierarchical regression for multiple comparisons in a case-control study of occupational risks for lung cancer
…suffer from false positive findings. Semi-Bayes adjustment methods have sometimes been used to address this issue. Hierarchical regression is a more general approach, including Semi-Bayes adjustment as a special case, that aims at improving…
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Medical study · Medical research · 2012
Asbestos fibre burden in the lungs of patients with mesothelioma who lived near asbestos-cement factories
…residence to both plants. To provide information on the intensity of environmental asbestos exposure, in the general population living around these factories, through the evaluation of the lung fibre burden in mesothelioma patients. We analysed by…
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Medical study · Medical research · 2014
A comparison of exposure assessment approaches: lung cancer and occupational asbestos exposure in a population-based case-control study
…assessment of occupational exposure to asbestos was compared using self-reports and a general population job-exposure matrix (DOM-JEM). Cases and frequency matched controls provided life-time job histories and self-reported exposures to potential…
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Medical study · Medical research · 2024
Lung Cancer Risks Associated with Occupational Exposure to Pairs of Five Lung Carcinogens: Results from a Pooled Analysis of Case-Control Studies (SYNERGY)
…the selected lung carcinogens resulted generally in higher risk than exposure to individual agents, highlighting the importance to reduce and control exposure to carcinogens in workplaces and the general environment. https://doi.org/10.1289/EHP13380.
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Medical study · Medical research · 2000
Multicentric study on malignant pleural mesothelioma and non-occupational exposure to asbestos
…A dose-response pattern appeared with intensity of both sources of exposure. It is suggested that low-dose exposure to asbestos at home or in the general environment carries a measurable risk of malignant pleural mesothelioma.