2 results for “Reaction Department”
-
Medical study · Medical research · 2013
T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
…His blood tryptase was markedly raised, which the authors said confirmed anaphylaxis, a severe allergic reaction. His IgG antibodies against mouse proteins rose after his earlier infusions, but tests for IgE antibodies against mouse serum proteins…
-
Medical study · Medical research · 2021
Mesothelin-targeted CAR-T cell therapy for solid tumors
…15. In the first trial in humans, one mesothelioma patient had a severe allergic reaction (anaphylaxis). A Memorial Sloan Kettering conference abstract reported results for 19 pleural mesothelioma patients given the cells into the chest. Of…