9 results for “Reaction Department”
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Medical study · Medical research · 1977
Immune adherence reactivity of rat alveolar macrophages following inhalation of crocidolite asbestos
…a statistically significant difference. Sheep red cells, which cannot take part in this reaction, stuck far less to macrophages from exposed rats. Treating the cells with antiserum against the complement component C3 reduced adherence to 4…
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Medical study · Medical research · 1998
Asbestos fibers and interleukin-1 upregulate the formation of reactive nitrogen species in rat pleural mesothelial cells
…polymerase chain reaction (RT-PCR), increased progressively from 2 to 12 h in IL-1beta-containing cultures. Nitrite (NO2-), the stable oxidation product of .NO in mesothelial cell conditioned medium, was assayed through the Griess reaction…
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Medical study · Medical research · 1992
A novel biotinylated probe specific for hyaluronate. Its diagnostic value in diffuse malignant mesothelioma
…staining for hyaluronate. Furthermore, the staining reaction was classed as moderate or greater in 26 mesotheliomas (79%), thus suggesting the utility of this probe in the differential diagnosis of malignant mesothelioma versus adenocarcinoma. We conclude that…
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Medical study · Medical research · 1994
Asbestos fibers and interferon-gamma up-regulate nitric oxide production in rat alveolar macrophages
…in macrophage conditioned medium, was assayed by the Griess reaction. Production of NO2- by AM was significantly increased by both chrysotile (P < 0.01) and crocidolite (P < 0.05) asbestos fibers (10 micrograms/ml…
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Medical study · Medical research · 1997
Pleural macrophage recruitment and activation in asbestos-induced pleural injury
…by scanning electron microscopy. Pleural macrophage supernatants were assayed for production of nitric oxide (NO) (by the Griess reaction) and tumor necrosis factor alpha (TNF-alpha) (by an enzyme-linked immunosorbent assay method). Significantly greater amounts…
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Medical study · Medical research · 1998
Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury
…reactive oxygen species (superoxide anion, hydrogen peroxide, hydroxyl radical formed through Fenton/Haber-Weiss reactions) and of reactive nitrogen species, in which nitric oxide reacts with superoxide to form peroxynitrite, an oxidant that nitrates tyrosine residues…
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Medical study · Medical research · 1977
Immunological studies of patients with asbestosis. I. Studies of cell-mediated immunity
…Cape crocidolite and amosite. On skin tests, reactions to tuberculin did not differ significantly between the groups. Five of 26 patients and no controls failed to react to Candida extract. Fourteen of 26 patients and 6…
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Medical study · Medical research · 1981
Asbestos inhalation and the induction of splenic lymphocytic proliferation in the rat
…The authors concluded that asbestos inhalation produced two distinct effects on the macrophages, one attributed to a putative asbestos-related neoantigen. They suggested immune reactions might contribute to asbestosis. The number of rats was not reported.
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Medical study · Medical research · 1981
Manifestations of cellular immunity in the rat after prolonged asbestos inhalation. II. Alveolar macrophage-induced splenic lymphocyte proliferation
…some respects, to the lymphoproliferative response evoked by sodium periodate-treated control macrophages, since both these reactions peaked at 72 hr and were abolished by treatment of the macrophages with the reducing agent, L-cysteine. This…