5 results for “Reaction Department”
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Medical study · Medical research · 2016
BAP1 Immunohistochemistry and p16 FISH in the Diagnosis of Sarcomatous and Desmoplastic Mesotheliomas
…help diagnose sarcomatous and desmoplastic mesotheliomas. These tumors can be hard to distinguish from organizing pleuritis, a benign reaction of the pleura. The authors tested tissue from 20 such pleural mesotheliomas, from 18 men and 2…
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Medical study · Medical research · 2018
New Insights on Diagnostic Reproducibility of Biphasic Mesotheliomas: A Multi-Institutional Evaluation by the International Mesothelioma Panel From the MESOPATH Reference Center
…the usefulness of FISH detection of CDKN2A(p16) HD compared to BAP1 loss on the spindle cell component for the separation in ambiguous cases between benign florid stromal reaction from true sarcomatoid component of biphasic mesothelioma…
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Medical study · Medical research · 2016
New Markers for Separating Benign From Malignant Mesothelial Proliferations: Are We There Yet?
This was a literature review of laboratory tests for telling malignant mesothelioma from benign mesothelial reactions. The authors wrote that five older stains (GLUT-1, p53, IMP-3, epithelial membrane antigen and desmin) worked only in…
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Medical study · Medical research · 2016
Utility of BAP1 Immunohistochemistry and p16 (CDKN2A) FISH in the Diagnosis of Malignant Mesothelioma in Effusion Cytology Specimens
…might also be useful in effusion cytology specimens, we examined 15 biopsies of epithelial mesotheliomas and 3 benign mesothelial reactions and corresponding effusion cytology paraffin-embedded cell blocks. Four cytology specimens were too scanty for p16…
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Medical study · Medical research · 2016
The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification
…Citing other studies, the authors described tests that showed promise but needed further confirmation. These included p16 FISH and BAP1 staining for separating mesothelioma from benign reactions, though neither finds every mesothelioma. They included a preliminary…