6 results for “Reaction Department”
-
Medical study · Medical research · 1986
Alveolar macrophage stimulation of lung fibroblast growth in asbestos-induced pulmonary fibrosis
…proliferation, and collagen deposition. To evaluate the potential involvement of alveolar macrophages in the subsequent fibrogenic reaction, the authors studied the effects of macrophages from normal and asbestos-treated rats upon lung fibroblast proliferation in vitro…
-
Medical study · Medical research · 1985
An assessment of the fibrogenic potential of very short 4T30 chrysotile by intratracheal instillation in rats
…structure, and surface charge, the lung tissue reaction differed considerably. Lungs of animals exposed to UICC chrysotile B showed significant pathological alterations as early as 7 days following treatment. The lesions were localized in and around…
-
Medical study · Medical research · 1989
Rat lung reactivity to natural and man-made fibrous silicates following short-term exposure
…more significantly to attapulgite and Fiberfrax although the tissue reaction differed considerably for these two materials. While attapulgite, at doses up to 10 mg caused minimal reactions characterized by mononuclear cell infiltration mainly in the alveolar…
-
Medical study · Medical research · 1985
Characterization of the bronchoalveolar cellular response in experimental asbestosis. Different reactions depending on the fibrogenic potential
This was an animal experiment in male Wistar rats. Each rat received a single injection into the windpipe of saline (control), 5 mg of UICC chrysotile B asbestos, or 5 mg of very short 4T30 chrysotile fibers. Lung washings (bronchoalveolar lavage)…
-
Medical study · Medical research · 1986
Cytokine regulation of lung fibroblast proliferation. Pulmonary and systemic changes in asbestos-induced pulmonary fibrosis
…later loss of the blood-cell inhibitor may be a consequence or amplifier of fibrosis. They noted that, given the injection method, their data do not relate to very early reactions to low-level inhaled asbestos.
-
Medical study · Medical research · 1983
Asbestos-related increase in pulmonary levels of vasoactive intestinal peptide (VIP)
…the pathogenesis of asbestos-related diseases. Exposure to asbestos causes chronic inflammatory reactions in the lung which may lead to fibrosis (1) and increase the incidence of pleuropulmonary cancers (2). Little is known concerning the biochemical…