2 results for “Reaction Department”
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Medical study · Medical research · 2013
Diagnostic usefulness of p16/CDKN2A FISH in distinguishing between sarcomatoid mesothelioma and fibrous pleuritis
…examination is inconclusive. We studied the usefulness of deletion of p16 with fluorescence in situ hybridization (FISH) and p16 hypermethylation with polymerase chain reaction for the diagnosis and prognosis of malignant pleural mesothelioma (MPM). We analyzed…
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Medical study · Medical research · 2010
Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus
…the tumor-specific midkine (Mdk) promoter could confer transcriptional targeting to oncolytic adenoviruses for effective treatment of malignant mesothelioma. We analysed Mdk expression by quantitative reverse transcription-polymerase chain reaction in six human mesothelioma cell lines…