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1 result for “Reaction Department”

1. Medical study · Medical research · 2013

   Metabolic response to pegylated arginine deiminase in mesothelioma with promoter methylation of argininosuccinate synthetase

   …1 (ASS1). Immunohistochemistry showed his tumor was ASS1-deficient, and methylation-specific polymerase chain reaction confirmed ASS1 promoter methylation. He was randomly assigned to 320 IU/m2/wk of ADI-PEG20 by intramuscular injection. After 3…