561 results for “Reaction Department”, page 28 of 29
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Medical study · Medical research · 1997
Pleural mesotheliomas have an integrin profile distinct from visceral carcinomas
…beta 1 and 4. SMM and the sarcomatoid elements of BMM (scBMM) reacted variably for alpha 1,3,5,6 and v, and beta1. Reactions for alpha3, found in all tumors, were strongest in EMM, ecBMM…
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Medical study · Medical research · 1981
Manifestations of cellular immunity in the rat after prolonged asbestos inhalation. II. Alveolar macrophage-induced splenic lymphocyte proliferation
…some respects, to the lymphoproliferative response evoked by sodium periodate-treated control macrophages, since both these reactions peaked at 72 hr and were abolished by treatment of the macrophages with the reducing agent, L-cysteine. This…
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Medical study · Medical research · 2005
Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells
…a chronic oxidative stress (i.e. smoke), it may behave as a prooxidant, propagating free radical-induced reactions, consuming endogenous antioxidants and inducing DNA oxidative damage. In this context, it may regulate cell growth and death…
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Medical study · Medical research · 1990
Microsomal lipid peroxidation and oxy-radicals formation are induced by insoluble iron-containing minerals
…two processes are mainly due to the presence of redox active iron at the surface of the solid particles and thus are greatly inhibited by desferrioxamine, a strong iron chelator. However, these reactions are not correlated.
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Medical study · Medical research · 1986
Studies on the role of oxygen radicals in asbestos-induced cytopathology of cultured human lung mesothelial cells
…after exposure to amosite asbestos, although oxygen radicals were readily detected in cells exposed to menadione, an uncoupler of oxidation-reduction reactions. Cellular thiol levels were reduced after exposure to menadione, but were not affected by…
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Medical study · Medical research · 2020
Sex Differences and Adverse Effects between Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer
…Patients (218) aged 40-80 years were treated with either chemotherapy or immunotherapy. Their response to treatment and any subsequent adverse drug reactions were studied. Results: 69% of patients were treated with chemotherapy and 31% were…
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Medical study · Medical research · 2021
Ongoing downplaying of the carcinogenicity of chrysotile asbestos by vested interests
…persisting strong influence of vested asbestos-related interests in workers and public health issues including regulations and compensation necessitate ongoing alertness, corrections and appropriate reactions in scientific as well as public media and policy advisory bodies.
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Medical study · Medical research · 2020
Sri Lanka: report on its children's environmental health
…air, and fungi, including moulds in poorly maintained buildings, can trigger asthma or cause allergic reactions and infections among children inhabiting these environments. In rural areas, chemicals were accountable for 30.2% of acute poisonings, with…
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Medical study · Medical research · 2016
Synchrotron X-ray microscopy reveals early calcium and iron interaction with crocidolite fibers in the lung of exposed mice
…inhaled asbestos fibers; (2) the extent of the deposition of these ions is proportionally directly related and (3) iron and calcium deposition on inhaled asbestos fibers is concomitant with the appearance of inflammatory and hyperplastic reactions.
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Medical study · Medical research · 2020
A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma
…mg/kg and used for cohort expansion. The most common treatment-related adverse events (AEs) were nausea (56%), decreased appetite (36%), infusion reactions (36%), decreased neutrophil counts (36%), and fatigue (33%). The confirmed ORR was 39%…
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Medical study · Medical research · 2000
Inorganic dust pneumonias: the metal-related parenchymal disorders
…of metals, is also discussed. Advances in our knowledge of antigen-specific immunologic reactions in the lung are particularly evident in disorders secondary to beryllium and nickel exposure, where immunologic mechanisms have been well characterized. For…
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Medical study · Medical research · 2004
Nursing considerations for administering pemetrexed (Alimta) in combination with cisplatin for malignant pleural mesothelioma
…the necessity of supplementation with folic acid and vitamin B12. As with all drugs, careful attention must be paid to patient selection, laboratory monitoring, contraindications, and appropriate interventions in the event of adverse reactions or overdose.
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Medical study · Medical research · 1981
Comparative pulmonary responses to inhaled inorganic fibers with asbestos and fiberglass
…rats and hamsters but not in guinea pigs. Fine fiberglass particles were not fibrogenic. Rats revealed more fibrogenic pulmonary reactions than guinea pigs or hamsters. A few pulmonary tumors developed in animals exposed to asbestos, Fybex…
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Medical study · Medical research · 1990
Asbestos and other toxins
…most significant factors in behavioral stability and coping. The author concluded that telling exposed workers the truth about their health appeared to reinforce their usual patterns of behavior rather than create new or non-adaptive reactions.
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Medical study · Medical research · 1998
Occupational illnesses within two national data sets
…sewing machine operators, and dentists. Mental disorders generated more morbidity than is generally acknowledged. Neurotic reactions to stress were highest in the transportation and public utility industries, as well as in finance, insurance, and real estate…
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Medical study · Medical research · 2008
10th Anniversary Critical Review: Naturally occurring asbestos
…as it has developed in the United States of America and elsewhere, including some superficial insights into the reactions of communities to the presence of NOA. These responses to 'contamination' by nature deserve further in-depth…
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Medical study · Medical research · 2014
Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes
…patchy parietal mesothelial proliferation lesions. In addition, MWCNT-L induced stronger inflammatory reactions including increased inflammatory cell number and cytokine/chemokine levels in the pleural cavity lavage than MWCNT-S. In contrast, MWCNT-S induced stronger…
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Medical study · Medical research · 2003
Bronchiolitis caused by occupational and ambient atmospheric particles
…hyperplasia, probably through oxidant mechanisms. These reactions are intrinsic properties of the particles and do not require exogenous inflammatory cells. There is considerable evidence that individuals with occupational exposure to a wide variety of mineral dusts…
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Medical study · Medical research · 1990
A comparative immunohistochemical study of peritoneal and ovarian serous tumors, and mesotheliomas
…However, since some PST do not stain for any of the three antibodies and the focal nature of positive reactions in some cases may be difficult to interpret, exclusion of mesotheliomas is enhanced by the use…
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Medical study · Medical research · 2018
Inflammation and cancer
…As an example, oxidatively damaged transferrin released iron ion, which may mediate Fenton reactions and generate additional reactive oxygen species. Dysfunction of anti-oxidative proteins due to this damage might increase oxidative stress. Such damage in…