985 results for “General Electric”, page 33 of 50
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Medical study · Medical research · 1990
Modulating factors in the expression of radiation-induced oncogenic transformation
…scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitative are also the least relevant in terms of human carcinogenesis and human risk estimation…
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Medical study · Medical research · 1995
Augmentation of chrysotile-induced oxidative stress by BHA in mice lungs
Asbestos is known to induce oxidative stress in the lung. The consumption of butylated hydroxyanisole (BHA) in preserved food and soft drinks is increasing in the general population, which includes workers in asbestos factories. Because there…
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Medical study · Medical research · 2013
Risk factors associated with asbestos-related diseases: a community-based case-control study
…is a first level carcinogen. However, few epidemiological studies analyse the risk and protective factors associated with asbestos-related diseases and follow up these conditions in the general population. Pleural mesothelioma, caused by inhalation of asbestos…
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Medical study · Medical research · 2012
Utility of a CEA, CD15, calretinin, and CK5/6 panel for distinguishing between mesotheliomas and pulmonary adenocarcinomas in clinical practice
…mesothelioma from pulmonary adenocarcinoma originated from academic centers or specialized immunohistochemistry laboratories, but little is known about how such stains perform in general practice laboratories. The Canadian Immunohistochemistry Quality Control program circulates tissue array slides to…
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Medical study · Medical research · 1981
The second diagnosis: the role of the pathologist in identifying pneumoconioses in lungs excised for tumor
This short review in the journal's Current Topics section, written by a lung pathologist at Massachusetts General Hospital, argued that pathologists examining lungs removed for tumor should also make a 'second diagnosis' of disease in…
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Medical study · Medical research · 2005
A cancer incidence and mortality study of Dow Chemical Canada Inc. manufacturing sites
…cancer incidence risk among chemical manufacturing sites. We followed 5277 men and 1301 women from 1950 to 1999. Employees experienced lower mortality and cancer incidence rates than the general population for several major causes of death…
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Medical study · Medical research · 2006
Identification of specific gene copy number changes in asbestos-related lung cancer
…vivo experiments have shown that asbestos can cause chromosomal damage and aberrations. Lung tumors, in general, have several recurrently amplified and deleted chromosomal regions. To investigate whether a distinct chromosomal aberration profile could be detected in…
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Medical study · Medical research · 2016
Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden
We have conducted a population-based study of pleural mesothelioma patients with occupational histories and measured asbestos lung burdens in occupationally exposed workers and in the general population. The relationship between lung burden and risk, particularly…
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Medical study · Medical research · 1993
Occupational lung cancer
Exposure to certain industrial agents has been thought to have carcinogenic potential, both for employees who work closely with such agents and for the general population that comes in contact with them. Although case reports, laboratory…
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Medical study · Medical research · 2018
Past and current asbestos exposure and future mesothelioma risks in Britain: The Inhaled Particles Study (TIPS)
…lung burdens in British birth cohorts from 1940 to 1992 were estimated for asbestos-exposed workers and the general population. Regression analysis of British mesothelioma death rates and average lung burdens in birth cohorts born before…
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Medical study · Medical research · 2018
The characteristics of asbestos-related disease claims made to the Korea Workers' Compensation and Welfare Service (KCOMWEL) from 2011 to 2015
…related disease from 2011 to 2015. Among these claims, we selected approved workers' compensation claims relating to malignant mesothelioma and lung cancer, and analyzed the general characteristics, exposure characteristics, pathological characteristics, and occupation and industry distribution…
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Medical study · Medical research · 2023
The amino-acid stress sensing eIF2α kinase GCN2 is a survival biomarker for malignant mesothelioma
…leading to new research for therapeutics which might exploit this potential vulnerability. We measured the levels of General Control Non-derepressible 2 (GCN2) protein in malignant mesothelioma tumour samples and determined whether these levels correlate with…
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Medical study · Medical research · 2022
Unusually Aggressive Presentation of Malignant Peritoneal Mesothelioma: Two Case Reports
…radiotherapy and/or intraperitoneal or systemic therapy. Prognosis depends on TNM stage and histologic subtype with epithelioid subtype being the most favorable one but in general remains poor. We present a 59-year-old male (patient…
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Medical study · Medical research · 2020
A clinical evaluation and tissue fiber burden analysis of a lifetime resident of Libby, Montana with adenocarcinoma of the lung
…lifelong resident of Libby and whose history of exposure was as a member of the general population there. To our knowledge this is the first time tissue from a member of the general population of Libby…
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Medical study · Medical research · 2024
Fusobacterium nucleatum-Induced Empyema Masquerading as Lung Cancer: A Diagnostic Challenge
…and fatigue. He was referred by a general practitioner for evaluation of a round lesion in the right lung. Chest computed tomography (CT) revealed a pleural-based mass and small right-sided pleural effusion that was…
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Medical study · Medical research · 2016
Comparison of SKIP expression in malignant pleural mesotheliomas with Ki-67 proliferation index and prognostic parameters
…3 ±12.2 years. The median overall survival period was 8.5 months. Factors negatively affecting general survival in the univariate analysis included high SKIP expression, Ki-67 proliferative index over 30%, presence of non-epithelioid…
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Medical study · Medical research · 2019
Characterization and assessment of the potential toxicity/pathogenicity of fibrous glaucophane
…in California for building/construction purposes (see for example the Calaveras Dam Replacement Project - CDRP). Dust generated by these excavation activities may expose workforces and the general population to this potential natural hazard. In this work…
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Medical study · Medical research · 2016
Mesothelioma among Motor Vehicle Mechanics: An Updated Review and Meta-analysis
…issue, we conducted a new systematic review and meta-analysis. A comprehensive PubMed literature search through May 2014 was conducted to identify studies that reported relative risk estimates for mesothelioma among motor vehicle mechanics (in general)…
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Medical study · Medical research · 2019
Monitoring of airborne asbestos fibers in an urban ambient air of Shahryar City, Iran: levels, spatial distribution, seasonal variations, and health risk assessment
…the time period of August 2017 and June 2018 to determine the concentration of asbestos fiber in the ambient air of Shahryar City and to evaluate their health effects for the general population of the city…
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Medical study · Medical research · 2020
Diffuse pleural thickening and thoracic contraction: An indistinguishable case from malignant pleural mesothelioma
…to take any kind of mesothelioma treatments. Four months later, she consented to a surgical pleural biopsy under general anesthesia to obtain larger tissue samples, which included typical proliferating polygonal cells positive for CAM5.2, calretinin…