3 results for “Reaction Department”
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Medical study · Medical research · 1989
Dusts causing pneumoconiosis generate .OH and produce hemolysis by acting as Fenton catalysts
…were studied. The authors tested whether dusts act as Fenton catalysts, turning hydrogen peroxide into damaging hydroxyl radicals, a reaction in which iron or other metals take part. With ascorbate (vitamin C) present, amosite, chrysotile and…
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Medical study · Medical research · 1984
Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide
…hydroxyl radicals from a normal byproduct of tissue metabolism, hydrogen peroxide. The iron chelator desferroxamine inhibits this reaction, indicating a major role for iron in the catalytic process, and suggesting a possible mechanism by which asbestos…
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Medical study · Medical research · 1989
Tobacco-borne siderophoric activity
…Indeed, elements in tobacco smoke and asbestos synergistically damage DNA through reactions mediated by the (probably iron-dependent) formation of hydroxyl radical. These considerations prompted the hypothesis that tobacco smoke might contain substances capable of "delocalizing…