5 results for “Reaction Department”
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Medical study · Medical research · 1984
Fiber localization and its relationship to lung reaction in rats after chronic inhalation of chrysotile asbestos
…with histologic changes indicating marked epithelial injury. Increased amounts of fibers are also localized in the lung interstitium with continued exposure to asbestos and are associated with a progressive interstitial fibrotic reaction. Following cessation of exposure…
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Medical study · Medical research · 1988
Progressive lung cell reactions and extracellular matrix production after a brief exposure to asbestos
…this would be the most likely site of a significant cellular or fibrotic reaction. The characteristics and progression of tissue reactions occurring at first alveolar duct bifurcations after a single brief asbestos exposure was defined using…
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Medical study · Medical research · 1985
Pathologic changes in the small airways of the guinea pig after amosite asbestos exposure
… where these fibers penetrated the airway walls, an interstitial inflammatory and fibrotic reaction (asbestosis) occurred. It is concluded that 1) amosite asbestos produces diffuse abnormalities throughout the noncartilagenous airways and possibly the cartilagenous airways as well…
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Medical study · Medical research · 1983
A murine model of asbestosis
…an initial macrophage reaction was found to progress to "asbestos body" formation and diffuse focal interstitial fibrosis within 1 year of a chronic exposure period. This reaction was most intense in areas adjacent to respiratory bronchioles…
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Medical study · Medical research · 1986
Alveolar macrophage stimulation of lung fibroblast growth in asbestos-induced pulmonary fibrosis
…proliferation, and collagen deposition. To evaluate the potential involvement of alveolar macrophages in the subsequent fibrogenic reaction, the authors studied the effects of macrophages from normal and asbestos-treated rats upon lung fibroblast proliferation in vitro…