145 results for “Reaction Department”, page 6 of 8
-
Court case · U.S. District Court, Eastern District of Texas · June 18, 1990 · in the opinion
Cimino v. Raymark Industries, Inc. (1990)
…Asbestos fibers, once inhaled, remain in place in the lung, causing a tissue reaction that is slowly progressive and irreversible. Typically, the disease does not manifest itself until years after initial exposure to asbestos fibers. The…
-
Court case · Pennsylvania Supreme Court · July 27, 1990 · in the opinion
JH France Refractories v. Allstate Insurance Co. (1990)
…organ, or the body itself. "Disease" is defined as occurring when "there is an injury and a response to that injury." The presence of asbestos in the lungs stimulates a wide range of reactions, which Dr…
-
Court case · Pennsylvania Superior Court · April 11, 1994 · in the opinion
DiDio v. Philadelphia Asbestos Corp. (1994)
…565a-566a, 571a-575a. James Didio testified that he suffers great anxiety as a result of his diagnosis and described his initial reaction to the diagnosis of his conditions as devastation. N.T. 9/20/91…
-
Court case · Maryland Court of Appeals · September 12, 1994 · in the opinion
US Gypsum v. Baltimore (1994)
…manufacturer has a continuing duty to warn of product defects discovered even long after the time of sale. Post-sale evidence relating to the hazards of asbestos-containing materials and the industry reaction was relevant, then…
-
Court case · New Jersey Superior Court, Appellate Division · April 29, 1993 · in the opinion
Owens-Illinois, Inc. v. United Ins. Co. (1993)
…produce significant pulmonary damage when inhaled. Instead, Vorwald reported that a "definite indication of tissue reaction appeared in the lungs of animals inhaling [\471] Kaylo dust." Moreover, prolonged exposure to the product, more than 30 months…
-
Court case · Pennsylvania Supreme Court · May 27, 1993 · in the opinion
JH France Refractories v. Allstate (1993)
…an organ, or the entire body. "Disease" means "an injury and a response to that injury." The presence of asbestos in the lungs stimulates a wide range of reactions, which Dr. Craighead divides into three responses…
-
Medical study · Medical research · 1993
Pathogenesis of mesothelial reactions to asbestos fibers. Monocyte recruitment and macrophage activation
Exposure to asbestos fibers leads to a variety of mesothelial reactions: pleural effusions, fibrotic pleural plaques, and malignant mesotheliomas. An animal model was developed to reproduce these lesions in C57B1/6 mice using weekly intraperitoneal injections…
-
Medical study · Medical research · 1998
Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury
…reactive oxygen species (superoxide anion, hydrogen peroxide, hydroxyl radical formed through Fenton/Haber-Weiss reactions) and of reactive nitrogen species, in which nitric oxide reacts with superoxide to form peroxynitrite, an oxidant that nitrates tyrosine residues…
-
Medical study · Medical research · 1992
The role of free radicals in asbestos-induced diseases
…this reactive radical. However, asbestos also appears to catalyze electron transfer reactions that do not require iron. Iron chelators either inhibit or augment asbestos-catalyzed generation of the hydroxyl radical and/or pathological changes, depending on…
-
Court case · U.S. Court of Appeals, Third Circuit · March 21, 1996
Holbrook v. Lykes Bros. SS Co., Inc. (1996)
…since diagnosis and cause were the central issues. It upheld the admission of the defense radiation experts and the redaction of mesothelioma references in records. It found no unfair judicial conduct and refused a new judge…
-
Medical study · Medical research · 1998
Medical thoracoscopic talc pleurodesis for chylothorax due to lymphoma: a case series
…day evaluation interval. Complications included medication reactions in two patients (8.3%) and ARDS in one patient (4.1%). Many patients with lymphoma-related chylothorax are refractory to chemotherapy and/or radiation therapy. In this group…
-
Medical study · Medical research · 1998
Reactive oxygen species: their relation to pneumoconiosis and carcinogenesis
…caused lung immune cells to release an inflammatory signaling protein (TNF-alpha), which the authors linked to metal-driven free radical reactions. The authors concluded that their studies support the hypothesis that ROS are involved in…
-
Medical study · Medical research · 1997
Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos
…in the same level of intracellular GSH depletion and efflux and the same decrease in gamma-GCS activity as treatment with unmodified crocidolite, which suggests that iron-catalyzed reactions were not responsible for the GSH depletion.
-
Medical study · Medical research · 1999
Role of transcription factor NF-kappaB in asbestos-induced TNFalpha response from macrophages
…were inhibited by oxygen radical scavengers and were enhanced by antioxidant enzyme inhibitors. These results indicate that asbestos-induced TNFalpha gene expression is mediated through a process that involves NF-kappaB activation and free radical reactions.
-
Medical study · Medical research · 1995
Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-alpha response from alveolar macrophages
…and for interleukin-1 alpha about 10-fold. The authors concluded that free radicals produced by iron-catalyzed reactions mediate asbestos-induced TNF-alpha gene expression and secretion. They noted that deferoxamine may not remove all…
-
Medical study · Medical research · 1994
The human evidence: parenchymal and pleural changes
Asbestos inhalation can cause fibrotic reactions both in the lung parenchyma and in the pleura. The incidence and relative proportions of these lesions in any cohort will be dependent on: (1) the time factor: both asbestosis…
-
Medical study · Medical research · 1994
Oxygen radicals and asbestos-mediated disease
Asbestos fibers are potent elaborators of active oxygen species whether by reactions involving iron on the surface of the fiber, or by attempted phagocytosis of fibers by cell types resident in the lung. The link between…
-
Medical study · Medical research · 1997
Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery
The purpose of this study was to determine the incidence and severity of thoracic reactions in patients undergoing intraperitoneal heated chemotherapy (IPHC). Forty-two patients who had intraperitoneal disseminated malignancies were treated with cytoreductive surgery (CS…
-
Medical study · Medical research · 1991
Radiological features of asbestos-related visceral pleural changes
…Generally, visceral pleural reactions follow the mesothelial cells response to various injurious substances, including asbestos, and even saline. The changes are nonspecific. They may occur subsequent to pleural reactions associated with many conditions, which include tuberculosis…
-
Medical study · Medical research · 1997
Pleural disease during treatment with bromocriptine in patients previously exposed to asbestos
Bromocriptine, which is used in the treatment of Parkinson's disease, can cause adverse pleuropulmonary reactions. Exposure to asbestos can result in similar lesions. Fifteen patients with former exposure to asbestos, who developed pleural fibrosis after…