15 results for “Reaction Department”
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Medical study · Medical research · 1996
Distinctive profile of alveolar macrophage-derived cytokine release induced by fibrogenic and nonfibrogenic mineral dusts
…BAL) for BAL cell populations and cytokine production in conjunction with histopathological assessment of lung tissue. Chrysotile B and short 4T30 chrysotile fibers induced chronic inflammatory reactions characterized by alveolar macrophage (AM) accumulation that resulted, respectively…
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Medical study · Medical research · 1996
Chrysotile inhibits glutathione-dependent protection against the onset of lipid peroxidation in rat lung microsomes
…investigated in vitro in rat lung microsomes. Addition of 1 mM glutathione to the above reaction system containing microsomes supplemented with vitamin E (1 nmol/mg protein) reduced lipid peroxidation. Similar protection by glutathione could be…
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Medical study · Medical research · 1998
Antiradical and chelating effects in flavonoid protection against silica-induced cell injury
Quercetin, dihydroquercetin, and rutin are capable of scavenging superoxide anion (rate constants of the reaction with superoxide at pH 10 were 1.7 x 10(5), 1.5 x 10(5), and 0.5 x 10…
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Medical study · Medical research · 1991
Preparation of radiolabeled bioactive asbestos fibers
…were radiolabeled successfully. Mild reaction conditions and short reaction times were found under which approximately 90% of the added 68Ge and 68Ga bound to the fibers. The radiolabel was retained even after washing the fibers extensively…
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Medical study · Medical research · 1995
Chrysotile asbestos stimulates platelet-derived growth factor-AA production by rat lung fibroblasts in vitro: evidence for an autocrine loop
…However, message amplification using a reverse transcriptase polymerase chain reaction allowed detection of the B-chain message. A significant dose-dependent mitogenic effect of asbestos was found by using both a cell proliferation assay and nuclear…
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Medical study · Medical research · 1999
Production of reactive oxygen intermediates by human macrophages exposed to soot particles and asbestos fibers and increase in NF-kappa B p50/p105 mRNA
…100 micrograms/10(6) cells) compared with control experiments (p < 0.01). Identical exposure conditions for BM resulted in a similar reaction pattern (maximum 2.2-fold increase in ROI release; p < 0.05)…
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Medical study · Medical research · 1994
Polyclonal human T-cell activation by silicate in vitro
…to silicate dust. T-cell receptor (TcR) V beta gene analysis on CD4- CD8- double-negative alpha beta T cells from scleroderma patients, using polymerase chain reaction (PCR), showed that certain V beta genes, V beta…
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Medical study · Medical research · 1994
Asbestos fibers and interferon-gamma up-regulate nitric oxide production in rat alveolar macrophages
…in macrophage conditioned medium, was assayed by the Griess reaction. Production of NO2- by AM was significantly increased by both chrysotile (P < 0.01) and crocidolite (P < 0.05) asbestos fibers (10 micrograms/ml…
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Medical study · Medical research · 1996
A study of the synergistic interaction of asbestos fibers with cigarette tar extracts for the generation of hydroxyl radicals in aqueous buffer solution
…This enhancement progressed with time, probably due to the reaction of the extracted iron with the slow released hydrogen peroxide from tar extracts. It was observed a fivefold increase in the ESR signal (for crocidolite and…
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Medical study · Medical research · 1992
Biphasic lung diffusing capacity: detection of early asbestos induced changes in lung function
…choice in subjects with an isolated decrease in DLCO. Exposure to asbestos can be associated not only with a reduction in DLCO, but also with a temporary increase in DLCO caused by a subclinical inflammatory reaction.
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Medical study · Medical research · 1995
Radiological changes in asbestos cement workers
…exposure variables. Progression was found long after the end of exposure. The findings on costophrenic angle obliterations, supposed to be sequelae of benign pleural effusions, were consistent with an immediate reaction triggered by intense asbestos exposure.
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Court case · U.S. Court of Appeals, Fifth Circuit · August 17, 1998 · in the opinion
Cimino v. Raymark Industries, Inc. (1998)
…the judge. When the proceedings resumed, the district court reprimanded plaintiffs' counsel. Pittsburgh Corning mentions adverse audience reaction on a couple of occasions, but the district court properly handled those matters. Neither of these occurrences, or…
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Court case · New Jersey Supreme Court · November 15, 1994 · in the opinion
Becker v. Baron Bros. (1994)
…motions, the court stated that its basis for ruling that asbestos products without warnings are defective as a matter of law was "pretty much \ \ \ judicial gut reaction and instinct as well as Beshada." On appeal, the…
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Medical study · Medical research · 1994
The human evidence: parenchymal and pleural changes
Asbestos inhalation can cause fibrotic reactions both in the lung parenchyma and in the pleura. The incidence and relative proportions of these lesions in any cohort will be dependent on: (1) the time factor: both asbestosis…
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Medical study · Medical research · 1998
Wollastonite fibers in vitro generate reactive oxygen species able to lyse erythrocytes and activate the complement alternate pathway
…ferric chloride and dithionite. In addition, ROS generation was partially inhibited (by 46-54%) in the reactions performed in the presence of 1,3-dimethyl-2-thiourea (DMTU), a strong hydroxyl radical scavenger. Wollastonite fibers were…