41 results for “Reaction Department”, page 1 of 3
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Court case · Maryland Court of Appeals · August 28, 1996 · in the opinion
Owens-Corning Fiberglas Corp. v. Garrett (1996)
…effect. That OCF had direct knowledge of the hazardous nature of asbestos was evident in 1941, when one of the lawyers in its Legal and Patent Department, having received a letter from a Saranac Doctor, expressed…
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Court case · New Jersey Superior Court, Appellate Division · June 5, 1995 · in the opinion
Ripa v. Owens-Corning Fiberglas (1995)
…Vorwald to Hazard suggesting that Kaylo produced an asbestosis-like reaction in the lungs and that "every precaution should be taken to minimize exposure of industrial employees." (9) The final confidential January 1952 project report concluding…
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Medical study · Medical research · 1999
SV40 large T-antigen and human pleural mesothelioma. Screening by polymerase chain reaction and tyramine-amplified immunohistochemistry
…sequences. In this study, we screened 28 Belgian mesothelioma tumour samples for the presence of SV40 LTag-like DNA and its gene product by polymerase chain reaction amplification, using the SV.for3/SV.rev primer set…
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Medical study · Medical research · 1998
Reactive mesothelial hyperplasia vs mesothelioma, including mesothelioma in situ: a brief review
This article was a review of how to tell reactive mesothelial hyperplasia, a benign reaction of the lining cells, from epithelial mesothelioma in biopsy tissue, and of the idea of mesothelioma in situ. It summarized the…
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Medical study · Medical research · 1999
Simian virus 40 is present in most United States human mesotheliomas, but it is rarely present in non-Hodgkin's lymphoma
…hamsters. In humans, SV40 has been detected in tumors of the first four types. Using the polymerase chain reaction (PCR), we tested 29 non-Hodgkin's lymphomas (intermediate and high-grade), 25 posttransplant lymphoproliferative disorders, and…
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Medical study · Medical research · 1996
Simian virus 40 large T antigen (SV40LTAg) primer specific DNA amplification in human pleural mesothelioma tissue
…and three reactive pleurae, and amplified by the polymerase chain reaction (PCR) using the primer pairs used previously on fresh frozen tissues-namely, the SV primer set directed at the LTAg gene sequence unique to SV40…
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Medical study · Medical research · 1990
Mesothelial proliferation due to asbestos and man-made fibres. Experimental studies on rat omentum
…in rats has proven to be an appropriate method controlling fibrogenicity and carcinogenicity of asbestos fibres and other fibrous dusts. We analyzed the reaction patterns of mesothelial cover layer to different natural mineral fibres (crocidolite, chrysotile…
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Medical study · Medical research · 1998
SV40-like DNA sequences in pleural mesothelioma, bronchopulmonary carcinoma, and non-malignant pulmonary diseases
…tumours, and 33 non-malignant samples) and 38 additional samples distant from tumours were studied for the occurrence of SV40-like DNA sequences by polymerase chain reaction (PCR) amplification followed by hybridization with specific probes. Sequences…
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Medical study · Medical research · 1999
VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours
…cell lines, 54 MPM tumours and five normal pleural tissues. Expression levels for receptors and ligands were assessed by semiquantitative reverse transcriptase polymerase chain reaction analysis. Microvessels were highlighted by immunohistochemical staining for factor VIII. The…
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Medical study · Medical research · 1998
Pathogenesis of experimentally induced asbestos mesothelioma in rats
…and small cells covering spaces over the ribs. Inflammatory reaction and permanent pathological regenerative processes were observed in the mesothelium during 24 months after inoculation of asbestos fibres. Different lesions which we regarded as preneoplastic or…
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Medical study · Medical research · 1997
Absence of p53 mutations in malignant mesotheliomas
…mesotheliomas. Thirteen malignant mesotheliomas collected over the preceding 12 yr and maintained in paraffin blocks were examined by polymerase chain reaction (PCR) followed by both single-strand conformation polymorphism (SSCP) and denaturing gradient-gel electrophoresis (DGGE)…
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Medical study · Medical research · 1998
Human mesotheliomas contain the simian virus-40 regulatory region and large tumor antigen DNA sequences
…40-induced hamster mesothelioma tumor H9A. Polymerase chain reaction primers were used to amplify various simian virus 40 large T-antigen regions including a 105-base pair amino terminus fragment, a 281-base pair carboxyl terminus…
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Medical study · Medical research · 1996
The calcium binding protein calretinin is a selective marker for malignant pleural mesotheliomas of the epithelial type
…adenomatous or solid) and by the epithelial component of the mixed tumours. The immunohistochemical reaction is specific and reproducible. The tissues of the pulmonary parenchyma and of the pleura are negative for calretinin except for the…
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Medical study · Medical research · 1992
A novel biotinylated probe specific for hyaluronate. Its diagnostic value in diffuse malignant mesothelioma
…staining for hyaluronate. Furthermore, the staining reaction was classed as moderate or greater in 26 mesotheliomas (79%), thus suggesting the utility of this probe in the differential diagnosis of malignant mesothelioma versus adenocarcinoma. We conclude that…
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Medical study · Medical research · 1998
Cytokine gene therapy or infusion as treatment for solid human cancer
…excretion was detectable. At each cycle vaccinia-IL-2 mRNA (SQ [semi-quantitative] reverse transcription polymerase chain reaction) was maximal 24-72 h following injection reduced at 8 days and faded by 21 days. No tumor…
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Medical study · Medical research · 1990
Reactive lesions of the pleura. Immunohistochemical characterization
…The antibodies Leu M1, HEA 125 and BMA 130c (against CEA) showed no reaction in subserosal and mesothelial cells. With the antibody HMFG 2, however, a weak reaction could be observed. A distinction between reactive and…
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Medical study · Medical research · 1999
Kaposi's sarcoma following malignant mesothelioma
…of mesothelioma diagnosis and preceded the onset of Kaposi' sarcoma with a time lapse of 13 months. HHV8 DNA was detected by polymerase chain reaction in lesional Kaposi's sarcoma but not within mesothelioma. By immunostaining…
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Medical study · Medical research · 1998
Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer
…gastrointestinal (GI) toxicity (nausea and vomiting) was also observed at 120 mg/m2. Three of 30 patients developed a hypersensitivity reaction. Six patients had grade 2 lung injury manifested by a persistent cough that required antitussives…
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Medical study · Medical research · 1990
Unusual granular reactivity for carcinoembryonic antigen in malignant mesothelioma
…biopsies and three cell blocks from pleural effusions. Four tumours were epithelial and one was bimorphic. Immunoelectron microscopy in one case showed reaction product mainly associated with cytoplasmic vesicles, possibly Golgi-derived, and rough endoplasmic reticulum…
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Medical study · Medical research · 1996
Ber-EP4 for differentiating adenocarcinoma from reactive and neoplastic mesothelial cells in serous effusions. Comparison with carcinoembryonic antigen, B72.3 and Leu-M1
…diagnosis of serous effusions. It has the advantage of high sensitivity and ease of interpretation because of the high percentage of tumor cells stained, characteristic membranous staining and lack of cross-reaction with background inflammatory cells.