124 results for “Reaction Department”, page 6 of 7
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Medical study · Medical research · 2004
Varying risk comparison elements: effects on public reactions
…found format variations swamped in their effect by concern about asbestos, with the absence of a narrative and the parental role being the only attributes that increased negative risk reactions. Multiple regression analyses found that multidimensionality…
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Medical study · Medical research · 2002
Stability and inoculation of risk comparisons' effects under conflict: replicating and extending the "asbestos jury" study by Slovic et al
This experiment studied reactions to risk comparisons, not asbestos disease. The author replicated and extended a 1990 experiment by Slovic and colleagues. Participants played jurors in a hypothetical school board lawsuit against an asbestos installer. Students…
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Medical study · Medical research · 2004
H2-rich fluids from serpentinization: geochemical and biotic implications
…or health outcomes were studied. Chrysotile was treated only as a mineral: as a component in the modeled reactions and as a form of serpentine that grows in rock pore space. The calculations assumed a fluid…
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Medical study · Medical research · 2000
Serologic responses in patients with malignant mesothelioma: evidence for both public and private specificities
…protein. Antibodies to topoisomerase II beta were found in 13 of 14 patients and in 6 of 16 volunteers, though the volunteers' reactions were generally weak. Antibodies to U2AF(65) were found in two patients. Each…
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Medical study · Medical research · 2004
Asbestos and the pleura: a review
…in pleural disease, laboratory research on how asbestos damages cells, and United States public policy. They described four benign pleural reactions (effusions, circumscribed plaques, diffuse pleural thickening and rounded atelectasis) as well as mesothelioma. Citing other…
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Medical study · Medical research · 2004
Pathogenesis of the eosinophilic pleural effusions
…pulmonary emboli, asbestos exposure, and drug reactions. Differences in the clinical features suggest that a variety of mechanisms operate to induce eosinophilic pleural inflammation and pleural fluid accumulation. Human and animal studies indicate that interleukin (IL…
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Medical study · Medical research · 2001
Localised spontaneous regression in mesothelioma -- possible immunological mechanism
…lobe. Blood samples from her last 11 months showed antibodies against mesothelioma. Two of these reactions faded and one stayed stable. The authors judged this strong circumstantial evidence linking the immune cells to the regression. They…
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Medical study · Medical research · 2003
Evaluation of the catalytic activity of lipases immobilized on chrysotile for esterification
…the Mucor javanicus preparation gave yields of 82%, 80%, 25% and 24% over four uses. The authors concluded that chrysotile with adsorbed lipases is a very attractive and viable alternative for enzyme reactions in organic solvents.
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Medical study · Medical research · 2003
beta1-integrin mediates asbestos-induced phosphorylation of AKT and ERK1/2 in a rat pleural mesothelial cell line
…In studies here, we examined signal transduction events associated with integrin-directed cell reactions triggered by crocidolite asbestos in the pleural mesothelial cell line 4/4 RM-4. Crocidolite fibres induced a significant time- and dose…
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Medical study · Medical research · 2003
Cell signaling and transcription factor activation by asbestos in lung injury and disease
…through receptor-mediated events or integrins. Alternatively, they may be stimulated by oxidants generated both during phagocytosis of minerals and/or by redox reactions on the mineral surface. Once initiated, these pathways can lead to promotion…
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Medical study · Medical research · 2000
Scanning electron microscopical investigations of broncho-alveolar casts after intratracheal asbestos fibre instillation
…the pleural space could not be explained satisfactorily. Histomorphological examinations showed that intratracheal instillation of asbestos fibres leads to parabronchial and intraalveolar granulomatous tissue reactions and bronchial epithelial regenerations. For further elucidation of the pathogenesis of…
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Medical study · Medical research · 2003
Long and short fiber amosite asbestos alters at a different extent the redox metabolism in human lung epithelial cells
…cells A549, long amosite fibers, more effectively than the short ones, initiate free radical reactions, inhibit the glucose 6-phosphate dehydrogenase activity and the pentose phosphate pathway, decrease the intracellular level of reduced glutathione, and increase…
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Medical study · Medical research · 2000
Role of Iron in the Cellular Effects of Asbestos
…investigations. Asbestos catalyzes many of the same reactions that iron does, including lipid peroxidation and DNA damage. At physiological pH, mobilization of iron from the fibers by a low-molecular-weight chelator greatly enhances these reactions…
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Medical study · Medical research · 2005
Respiratory toxicity of multi-wall carbon nanotubes
…inflammation and fibrosis biochemically and histologically. CNT and ground CNT were still present in the lung after 60 days (80% and 40% of the lowest dose) and both induced inflammatory and fibrotic reactions. At 2 months…
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Medical study · Medical research · 2007
Imatinib mesylate inhibits fibrogenesis in asbestos-induced interstitial pneumonia
…growth factor receptor (PDGFR) and c-Kit tyrosine kinases, has been shown to inhibit fibrosis and profibrotic signaling in mouse models of inflammation-mediated lung reactions. The authors tested imatinib mesylate in vivo in a mouse…
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Medical study · Medical research · 2005
Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells
…a chronic oxidative stress (i.e. smoke), it may behave as a prooxidant, propagating free radical-induced reactions, consuming endogenous antioxidants and inducing DNA oxidative damage. In this context, it may regulate cell growth and death…
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Medical study · Medical research · 2000
Inorganic dust pneumonias: the metal-related parenchymal disorders
…of metals, is also discussed. Advances in our knowledge of antigen-specific immunologic reactions in the lung are particularly evident in disorders secondary to beryllium and nickel exposure, where immunologic mechanisms have been well characterized. For…
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Medical study · Medical research · 2004
Nursing considerations for administering pemetrexed (Alimta) in combination with cisplatin for malignant pleural mesothelioma
…the necessity of supplementation with folic acid and vitamin B12. As with all drugs, careful attention must be paid to patient selection, laboratory monitoring, contraindications, and appropriate interventions in the event of adverse reactions or overdose.
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Medical study · Medical research · 2008
10th Anniversary Critical Review: Naturally occurring asbestos
…as it has developed in the United States of America and elsewhere, including some superficial insights into the reactions of communities to the presence of NOA. These responses to 'contamination' by nature deserve further in-depth…
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Medical study · Medical research · 2003
Bronchiolitis caused by occupational and ambient atmospheric particles
…hyperplasia, probably through oxidant mechanisms. These reactions are intrinsic properties of the particles and do not require exogenous inflammatory cells. There is considerable evidence that individuals with occupational exposure to a wide variety of mineral dusts…