1,676 results for “General Electric”, page 41 of 84
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Medical study · Medical research · 2014
Establishing a panel of chemo-resistant mesothelioma models for investigating chemo-resistance and identifying new treatments for mesothelioma
…transporter genes were greatly elevated in parental II-45 cells; verapamil, a general ABC transporter inhibitor, significantly increased sensitivity of vinorelbine-resistant cells to vinorelbine and pemetrexed-resistant cells to pemetrexed. Homozygous deletion of Cdkn2a/2b…
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Medical study · Medical research · 2017
Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study
…sampled in 2011 to 2014. None had a malignant disease when blood was drawn. The men came from the general population, not from a cohort of asbestos workers. The authors looked for factors linked to positive…
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Medical study · Medical research · 2019
Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines
…72 carriers (11%), at a median age of 60 years, compared with a median of 74 years in the general Dutch population. Six of these were pleural and two peritoneal. Nine more mesotheliomas were reported in…
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Medical study · Medical research · 2013
The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma
…9), compared with 14.8 months (95% CI 5.8 to 23.7) for those with high Axl. This link held after adjusting for factors including performance status (general fitness), low albumin and anaemia. In the…
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Medical study · Medical research · 2010
Cancer mortality in a surveillance cohort of German males formerly exposed to asbestos
…been exposed to chrysotile. Through April 30, 2007, 128 men died. Compared with German men in general, overall deaths were lower than expected (SMR 0.59, 95% CI 0.49-0.70). However, 15 men died…
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Medical study · Medical research · 2012
Occupational exposures to asbestos, polycyclic aromatic hydrocarbons and solvents, and cancers of the oral cavity and pharynx: a quantitative literature review
…risk. On the other hand, no association was found with exposure to solvents in general (meta-RR 0.98; 95% CI 0.77-1.23) but the strong heterogeneity between studies suggested differences in exposures. The…
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Medical study · Medical research · 2011
Comparison of exposure assessment methods for occupational carcinogens in a multi-centre lung cancer case-control study
…re-applied to all study subjects. Third, an independent general population JEM (GPJEM) was created by occupational exposure experts not involved in the original study, and applied to study subjects. Results from these methods were compared…
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Medical study · Medical research · 2013
Commentary on: Comparison of chest digital tomosynthesis and chest radiography for detection of asbestos-related pleuropulmonary disease
…a slight increase in radiation dose, described as possibly one to two times that of a conventional chest radiograph. Citing other published work about lung nodules in general, not asbestos disease, the author noted that DTS…
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Medical study · Medical research · 2012
Descriptive analysis of the respiratory health status of persons exposed to Libby amphibole asbestos
…Questionnaire total score was 38.5 (0 best, 100 worst), versus 8.41 in a Spanish general-population sample. Ever-smokers scored significantly worse on the questionnaire. The authors noted the cross-sectional design and insensitive…
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Medical study · Medical research · 2010
Attributable risk in men in two French case-control studies on mesothelioma and asbestos
…B. After weighting subjects according to distribution of socio-economic status in the general population for controls and according to distribution of socio-economic status of cases registered by the French National Mesothelioma Surveillance Program, re…
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Medical study · Medical research · 2012
Mesothelioma not associated with asbestos exposure
…peritoneal MM in five countries. They also cited a study of 2567 five-year survivors of Hodgkin lymphoma in which irradiated patients had almost 30-fold the general population's MM risk. For carbon nanotubes they…
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Medical study · Medical research · 2014
Evaluation of take-home exposure and risk associated with the handling of clothing contaminated with chrysotile asbestos
…weekly). These averages assumed zero asbestos outside the 30 to 45 minutes of each activity. PCM, a general fiber count, read 2 to 50 times higher than TEM, which the authors attributed largely to clothing fibers…
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Medical study · Medical research · 2011
Asbestos-related cancer risk in patients with asbestosis or pleural plaques
…Among asbestos-exposed individuals, those having radiographic evidence of pleural plaques are at increased risk for lung cancer and pleural mesothelioma, compared to the general population. However, there is no evidence that pleural plaque confers an…
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Medical study · Medical research · 2012
Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure
…exposure route. One day after a single LA dose, two 'acute phase' proteins, part of a general reaction to inflammation, rose in all three strains tested. Lipocalin-2 also rose in those three strains, but osteopontin…
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Medical study · Medical research · 2012
Adjuvant radiotherapy for malignant pleural mesothelioma: challenges and pitfalls
…almost exclusively epithelial tumors. Their median age was 57.8 years, compared with a median age at diagnosis of 68 years in the general malignant pleural mesothelioma population in Italy. In that series, 55.4% had…
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Medical study · Medical research · 2016
Comprehensive review of BAP1 tumor predisposition syndrome with report of two new cases
…13 with peritoneal disease were female. Median age at mesothelioma onset was 56 years, compared with a general-population figure of 74 that the authors cited. In the new families, the two index patients developed mesothelioma…
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Medical study · Medical research · 2012
Identification of miRNA-103 in the cellular fraction of human peripheral blood as a potential biomarker for malignant mesothelioma--a pilot study
…pleural mesothelioma, 17 cancer-free people formerly exposed to asbestos, and 25 volunteers from the general population. A screen of 328 microRNAs in patients and asbestos-exposed controls found 49 that differed at least threefold. Only…
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Medical study · Medical research · 2014
The four most pernicious myths in asbestos litigation: Part I: safe chrysotile and idiopathic mesothelioma
…data on a Connecticut friction-products factory cohort. On idiopathic mesothelioma, the author cited reviews of historical autopsy records at Massachusetts General Hospital and Mount Sinai Hospital. The author concluded that virtually all, if not all…
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Medical study · Medical research · 2013
The dog didn't bark
…prophylactic pleurodesis, typically for recurrent spontaneous pneumothorax. The author noted that these patients had then risked the 'normal' exposure to asbestos fibers suffered by the general population. The author pointed out that a different paper, by…
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Medical study · Medical research · 2014
History and evolution of warning labels for automotive friction products
…manual and on 1973 Bendix brake boxes. Later Ford, General Motors and Buick materials warned against compressed air and dry cleaning, and a 1993 Ford bulletin recommended non-asbestos parts. They reported that OSHA rules exempted…