7 results for “Owens-Illinois”
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Medical study · Medical research · 2017
Loss of BRCA1-associated protein 1 (BAP1) expression is rare in non-small cell lung cancer
This laboratory study, by Vancouver pathologists, asked how often non-small cell lung cancer (NSCLC) loses a protein called BAP1. Loss of BAP1 on tissue staining helps pathologists diagnose malignant mesothelioma, so the authors wanted to know how…
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Medical study · Medical research · 2018
Dosimetry of inhaled elongate mineral particles in the respiratory tract: The impact of shape factor
This article was an overview of a computer model, the multi-path particle dosimetry (MPPD) model version 3.04, with example simulations of how elongate mineral particles (EMPs), a group that includes asbestos fibers, are breathed in and deposited in…
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Medical study · Medical research · 2019
Refining classification of malignant pleural mesothelioma reveals its Achilles' heel
…gene-activity results were checked against protein levels in a replication series. The author concluded that the present classification cannot predict the most effective treatments and that the study opens a window for new targeted treatments.
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Medical study · Medical research · 2011
Ban asbestos phenomenon: the winds of change
The shift in the public perception of asbestos from "magic mineral" to "deadly dust" owes much to the mobilization by asbestos victims, ban-asbestos activists, health and safety campaigners, and individuals concerned about the global asbestos…
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Medical study · Medical research · 2012
Differences and similarities between carbon nanotubes and asbestos fibers during mesothelial carcinogenesis: shedding light on fiber entry mechanism
The emergence of nanotechnology represents an important milestone, as it opens the way to a broad spectrum of applications for nanomaterials in the fields of engineering, industry and medicine. One example of nanomaterials that have the…
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Medical study · Medical research · 2019
Pemetrexed-loaded nanoparticles targeted to malignant pleural mesothelioma cells: an in vitro study
…is more effective than Pe alone in inhibiting MPM cell line malignant phenotype. The innovative use of specifically targeted GNPs opens the perspective of local intrapleural administration to avoid normal cell toxicity and enhance chemotherapy efficacy.
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Medical study · Medical research · 2018
Tumor-specific genetic variants can be detected in circulating cell-free DNA of malignant pleural mesothelioma patients
…time the presence of ctDNA within circulating DNA of treatment naïve MPM patients. This finding opens perspectives towards the use of ctDNA as a biomarker for (early and differential) diagnosis, treatment and treatment monitoring of MPM…