8 results for “Reaction Department”
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Medical study · Medical research · 2011
A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials
The most common causes of granulomatous inflammation are persistent pathogens and poorly-degradable irritating materials. A characteristic pathological reaction to intratracheal instillation, pharyngeal aspiration, or inhalation of carbon nanotubes is formation of epithelioid granulomas accompanied by…
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Medical study · Medical research · 2011
A₃ receptors are overexpressed in pleura from patients with mesothelioma and reduce cell growth via Akt/nuclear factor-κB pathway
…between adenosine and MM, the presence and functionality of ARs were explored in human healthy mesothelial cells (HMC) and in malignant mesothelioma cells (MMC). ARs were analyzed by using reverse transcriptase-polymerase chain reaction, Western blotting…
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Medical study · Medical research · 2018
Fibrous nanocellulose, crystalline nanocellulose, carbon nanotubes, and crocidolite asbestos elicit disparate immune responses upon pharyngeal aspiration in mice
…BAL cells. The results revealed that pulmonary exposure to fibrous materials led to discrete local immune cell polarization patterns with a TH2-like response caused by ASB and TH1-like immune reaction to NCF, while CNT…
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Court case · Texas Court of Appeals · December 19, 2019 · in the opinion
Union Carbide Corporation v. Torres (2019)
…the inhalation of asbestos fibers and the penetration of the fibers through the air sac of the lung. He explained that the body's inflammatory reaction to the fibers causes genetic damage. As the damage accumulates…
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Medical study · Medical research · 2013
Cytotoxicity induced by exposure to natural and synthetic tremolite asbestos: an in vitro pilot study
…the etiology of the pathological effects of asbestos, cellular reactions to natural and synthetic asbestos fibers were compared using a lung alveolar cancer cell line (A549 epithelial cells), considered the first target of inhaled micro-environmental…
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Medical study · Medical research · 2015
A Single Aspiration of Rod-like Carbon Nanotubes Induces Asbestos-like Pulmonary Inflammation Mediated in Part by the IL-1 Receptor
…product development and potential risks on health. We investigated the difference of two different CNT and asbestos in inducing proinflammatory reactions in C57BL/6 mice after single pharyngeal aspiration exposure. We used long tangled and long…
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Medical study · Medical research · 2018
Persistent Pleural Lesions and Inflammation by Pulmonary Exposure of Multiwalled Carbon Nanotubes
…spraying, the rats were sacrificed for histological examination of the lung and chest wall; pleural cavity lavage was also collected at sacrifice for observation of pleural inflammatory reactions. The results indicated that intratracheally sprayed MWCNTs, like…
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Medical study · Medical research · 2016
Synchrotron X-ray microscopy reveals early calcium and iron interaction with crocidolite fibers in the lung of exposed mice
…inhaled asbestos fibers; (2) the extent of the deposition of these ions is proportionally directly related and (3) iron and calcium deposition on inhaled asbestos fibers is concomitant with the appearance of inflammatory and hyperplastic reactions.