26 results for “General Electric”, page 1 of 2
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Medical study · Medical research · 1994
Chrysotile biopersistence in the lungs of persons in the general population and exposed workers
…form, with both fibers and fibrils > 5 microns in length. Comparison of the lung fiber content of occupationally exposed persons with that of the general population showed marked qualitative and quantitative differences. Fibers are durable…
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Medical study · Medical research · 2011
Meeting report: mode(s) of action of asbestos and related mineral fibers
Although asbestos in general is well known to cause a range of neoplastic and non-neoplastic human health effects, not all asbestos fiber types have the same disease-causing potential, and the mode of action (MOA…
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Medical study · Medical research · 2010
Are current or future mesothelioma epidemics in Hong Kong the tragic legacy of uncontrolled use of asbestos in the past?
This ecologic study examined mesothelioma in Hong Kong's general population. It used Hong Kong Cancer Registry records and asbestos trade figures (all fiber types combined, per person per year, 1960–2006). From 1976 to 2006…
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Medical study · Medical research · 1990
Human disease consequences of fiber exposures: a review of human lung pathology and fiber burden data
…medians, except one study reporting only a mean), extremely high compared with general-population background levels. The reviewed studies indicated that mesothelioma may occur with fiber burdens considerably lower than those needed to produce asbestosis. One…
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Medical study · Medical research · 2010
The case for a global ban on asbestos
…cancer and mesothelioma. They described industry-sponsored "product defense" science. They cited a court document stating that General Motors, Ford and Chrysler paid almost $37 million between 2001 and 2008 to scientist-consultants. They reported that…
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Medical study · Medical research · 1997
Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos
…hour in that medium, so the authors suggested it was released from the cells continuously. They found no sign of general membrane damage. Activity of the enzyme gamma glutamylcysteine synthetase fell by 47%, while four other…
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Medical study · Medical research · 1974
Asbestos bodies and fibers in lung tissues
…lung from 14 people with pleural mesothelioma, 11 with severe occupational asbestosis with lung fibrosis and squamous carcinoma, and 52 unselected patients from the general population. By light microscopy, all unselected patients had a few asbestos…
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Medical study · Medical research · 1974
The subject of continuous vigilance
…has brought with it concomitant and widespread contamination of the environment. The need to control asbestos is required in the forms of legislation and surveillance, to prevent the spread of asbestos disease into the general population.
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Medical study · Medical research · 2000
Reducing environmental risk associated with laboratory decommissioning and property transfer
…b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been…
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Medical study · Medical research · 2010
A case-control study of lung cancer nested in a cohort of European asphalt workers
…risk. A sizable proportion of the excess mortality from lung cancer relative to the general population observed in the earlier cohort phase is likely attributable to high tobacco consumption and possibly to coal tar exposure, whereas…
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Medical study · Medical research · 1983
Assessment of the epidemiological data relating lung cancer to air pollution
…cancer likely greater than zero but unlikely to exceed 2% of all lung cancers, or 5 per 100,000 cases in urban males. The author concluded there was no reason to repeat such general-population studies.
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Medical study · Medical research · 1980
Clinical observations following asbestos exposure
…of mesothelioma in workers who did not handle asbestos directly and in household contacts. The author concluded that further investigation is needed to define the risk from long-term, low-level exposure in the general population.
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Medical study · Medical research · 1986
Contribution of environmental fibers to respiratory cancer
…large. Using a KL of 0.01, the authors estimated fewer than 100 lung cancers and 100 mesotheliomas per year in the general population from past ambient exposures. They noted great uncertainty in these estimates. They…
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Medical study · Medical research · 1985
Health implications of environmental exposure to asbestos
…about 2 per million per annum and that--as at least some mesothelioma cases in females are directly or indirectly attributable to occupational exposure--there is little room left for any contribution from the general environment…
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Medical study · Medical research · 1981
Extrapolation from occupational studies: a substitute for environmental epidemiology
Extrapolation from occupational data to general environmental exposures gives some interesting results, and these results might be useful in our decision-making process. These results could never be observed by environmental epidemiology and this method probably…
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Medical study · Medical research · 1997
Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis
…effective. Therefore, a key to reducing the mortality rate of this neoplasm is knowledge of the general sequence of genetic events between initiation of mesothelial cells and the emergence of the metastatic tumor cells. Unfortunately, relatively…
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Medical study · Medical research · 1990
Modulating factors in the expression of radiation-induced oncogenic transformation
…scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitative are also the least relevant in terms of human carcinogenesis and human risk estimation…
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Medical study · Medical research · 1997
Dose-response relationship of fibrous dusts in intraperitoneal studies
…90%, the hypothesis of a common slope of dose-response relationships (parallel probit lines in probit analysis) cannot be rejected. In general, parallelism of probit lines is considered an indication of a common mode of action…
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Medical study · Medical research · 2011
Occupational exposure to asbestos and ovarian cancer: a meta-analysis
…authors independently abstracted data; any disagreement was resolved by consulting a third reviewer. All but one study reported standardized mortality ratios (SMRs) comparing observed numbers of deaths with expected numbers for the general population; the exception…
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Medical study · Medical research · 1974
Inorganic particles of agricultural origin
…the mineral carriers (and active agents) will occur among pesticide application personnel and some proportion of the general population in the vicinity of pest control operations-to the extent that particle size of the disseminated material…