2 results for “Reaction Department”
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Medical study · Medical research · 1983
Reaction of rat lungs to inhaled chrysotile asbestos following acute and subchronic exposures
In this animal experiment, Fischer 344 rats breathed chrysotile asbestos from Quebec in inhalation chambers at an average respirable mass of 9.06 plus or minus 1.83 mg/m3. Male rats were exposed for 1 hour, 7 hours, or 7 hours a day for 5 days. Four…
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Medical study · Medical research · 2007
Imatinib mesylate inhibits fibrogenesis in asbestos-induced interstitial pneumonia
…growth factor receptor (PDGFR) and c-Kit tyrosine kinases, has been shown to inhibit fibrosis and profibrotic signaling in mouse models of inflammation-mediated lung reactions. The authors tested imatinib mesylate in vivo in a mouse…