5 results for “Reaction Department”
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Medical study · Medical research · 2019
Iron from a geochemical viewpoint. Understanding toxicity/pathogenicity mechanisms in iron-bearing minerals with a special attention to mineral fibers
…and the experimental methods used for their study. Special attention is devoted to the Fenton-like chain reaction involving Fe2+ in the formation of highly reactive hydroxyl radicals. The final part of this review deals with…
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Medical study · Medical research · 2009
Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
…Moreover, BC and BCM were able to increase (.)OH formation from H(2)O(2) in the Fenton reaction (determined by electron spin resonance spectroscopy). Addition of Vit A and RA to lung epithelial cells that…
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Medical study · Medical research · 1996
A study of the synergistic interaction of asbestos fibers with cigarette tar extracts for the generation of hydroxyl radicals in aqueous buffer solution
…This enhancement progressed with time, probably due to the reaction of the extracted iron with the slow released hydrogen peroxide from tar extracts. It was observed a fivefold increase in the ESR signal (for crocidolite and…
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Medical study · Medical research · 1992
The role of free radicals in asbestos-induced diseases
…this reactive radical. However, asbestos also appears to catalyze electron transfer reactions that do not require iron. Iron chelators either inhibit or augment asbestos-catalyzed generation of the hydroxyl radical and/or pathological changes, depending on…
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Medical study · Medical research · 2019
Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: Toward the era of mesothelioma prevention
…caused by modern industrial development. The major pathogenic mechanisms include oxidative stress either via catalytic reactions against the asbestos surface or frustrated phagocytosis of macrophages, and specific adsorption of hemoglobin and histones by asbestos fibers in…