13 results for “Reaction Department”
-
Medical study · Medical research · 1986
Keratin and epithelial membrane antigen immunoreactivity in nonneoplastic fibrous pleural lesions: implications for the diagnosis of desmoplastic mesothelioma
…EMA stained five of ten plaques and four of 11 lesions. Keratin also stained the fibrous reaction around six of eight metastases. Benign localized fibrous mesotheliomas and 16 fibrous lesions away from the pleura did not…
-
Medical study · Medical research · 2003
Asbestos bodies: clues to the mechanism of asbestos toxicity?
…lung, ascorbate was oxidized to oxalate in the presence of H2O2, a reaction inhibited by the iron chelator deferoxamine. The author called this a novel mechanism that may contribute to the pathogenicity of asbestos fibers. Oxidation…
-
Medical study · Medical research · 1983
Small-airway lesions in patients exposed to nonasbestos mineral dusts
…which they call mineral dust airways disease, is a nonspecific reaction of the small airways to inorganic particulates. The presence of such changes casts considerable doubt on the theory that small-airway abnormalities in asbestos workers…
-
Medical study · Medical research · 2012
Unusual DNA mismatch repair-deficient tumors in Lynch syndrome: a report of new cases and review of the literature
Immunohistochemical detection of DNA mismatch repair proteins and polymerase chain reaction detection of microsatellite instability have enhanced the recognition of mismatch repair-deficient neoplasms in patients with Lynch syndrome and, consequently, led to the identification of…
-
Medical study · Medical research · 2019
Chronic follicular pleuritis: a B cell-rich form of nonspecific pleuritis/fibrosis
…pleuritis/fibrosis (NSP) is rendered. The histology of this reaction has not been well described including a pattern of B cell lymphoid hyperplasia described as "chronic follicular pleuritis (CFP)". Thirty-two cases of NSP were studied…
-
Medical study · Medical research · 2012
Expression of the Ets transcription factor EHF in serous ovarian carcinoma effusions is a marker of poor survival
…using quantitative real-time polymerase chain reaction. Expression levels of EHF in ovarian carcinoma were additionally investigated for association with clinicopathologic parameters and survival. Quantitative real-time polymerase chain reaction analysis showed significantly higher expression of…
-
Medical study · Medical research · 1987
Congenital polycystic tumor of the atrioventricular node (endodermal heterotopia, mesothelioma): a histogenetic appraisal with evidence for its endodermal origin
…similar distribution to that of the argyrophil cells. A positive reaction of different distribution from that of the argyrophil cells was noted in a varying number of tubule-lining cells for carcinoembryonic antigen, epithelial membrane antigen…
-
Medical study · Medical research · 1983
Keratin proteins and carcinoembryonic antigen in lung carcinoma: an immunoperoxidase study of fifty-four cases, with ultrastructural correlations
…all squamous cell carcinomas. This reaction was particularly helpful in identifying squamous differentiation in poorly differentiated areas and in cases in which tonofilaments appeared to be sparse or absent on electron microscopy. Weak focal staining for…
-
Medical study · Medical research · 2003
Oxalate deposition on asbestos bodies
…vitro generated approximately 42 nmol of oxalate in 24 hours. Oxalate generation was diminished significantly by the inclusion of either deferoxamine or dimethylthiourea in the reaction mixture. Incubation of asbestos bodies and uncoated fibers isolated from…
-
Medical study · Medical research · 1990
Unusual granular reactivity for carcinoembryonic antigen in malignant mesothelioma
…biopsies and three cell blocks from pleural effusions. Four tumours were epithelial and one was bimorphic. Immunoelectron microscopy in one case showed reaction product mainly associated with cytoplasmic vesicles, possibly Golgi-derived, and rough endoplasmic reticulum…
-
Medical study · Medical research · 1997
Immunolocalization of integrins in the normal lung and in pulmonary carcinomas
…whereas reactions for alpha5 and alpha(v) were weaker and uneven; the remaining integrin subunits were not detected. Bronchial and bronchiolar epithelium showed variably intense staining for alpha2.3,6,v and beta1,4. Reactions were…
-
Medical study · Medical research · 1997
Pleural mesotheliomas have an integrin profile distinct from visceral carcinomas
…beta 1 and 4. SMM and the sarcomatoid elements of BMM (scBMM) reacted variably for alpha 1,3,5,6 and v, and beta1. Reactions for alpha3, found in all tumors, were strongest in EMM, ecBMM…
-
Medical study · Medical research · 1990
A comparative immunohistochemical study of peritoneal and ovarian serous tumors, and mesotheliomas
…However, since some PST do not stain for any of the three antibodies and the focal nature of positive reactions in some cases may be difficult to interpret, exclusion of mesotheliomas is enhanced by the use…