5 results for “Reaction Department”
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Medical study · Medical research · 2016
SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma
…molecular targets for the development of more effective therapies for MPM. Using quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) and an RNA interference-based screening, we examined the SORORIN gene as potential therapeutic targets for…
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Medical study · Medical research · 2016
Kinesin family members KIF11 and KIF23 as potential therapeutic targets in malignant pleural mesothelioma
…and new molecular targets for treatments are urgently needed. Using quantitative reverse transcription-polymerase chain reaction (RT-PCR) and an RNA interference-based screening, we screened two kinesin family members as potential therapeutic targets for MPM…
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Medical study · Medical research · 1996
Comparative analysis of p16/CDKN2, p53 and ras gene alterations in human non-small cell lung cancers, with and without associated pulmonary asbestosis
…were examined for genetic abnormalities of p16/CDKN2, p53 and ras genes by single-strand conformation polymorphism analysis of polymerase chain reaction products (PCR-SSCP) and direct sequencing. Ten specimens were obtained from autopsies in which…
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Medical study · Medical research · 2001
K-ras and rho A mutations in malignant pleural effusion
…and have been proposed to be a prognostic factor. The K-ras mutation in codon 12 is detectable even in cell-free fluids by using the enriched polymerase chain reaction (PCR) technique. On the other hand…
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Medical study · Medical research · 2011
Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins
The T cell line HOZOT has a unique FOXP3+CD4+ CD8+CD25+ phenotype, exhibits suppressive activity in allogeneic mixed lymphocyte reactions (MLR), and produces IL-10, defining HOZOT as regulatory T cells (Tregs). Interestingly, in addition…