3 results for “General Electric”
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Medical study · Medical research · 2001
Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer
…NSCLC). One hundred and eighty-five patients diagnosed with NSCLC undergoing surgical resection from June, 1992 through December, 1996 at Massachusetts General Hospital participated in this study. Methylation-Specific PCR (MSP), performed using fresh-frozen tissue…
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Medical study · Medical research · 2004
Growth inhibition and induction of apoptosis in mesothelioma cells by selenium and dependence on selenoprotein SEP15 genotype
…Reducing SEP15 in a sensitive line made it less responsive. The variant's distribution did not differ statistically significantly between blood from 36 mesothelioma patients and 48 people from the general population. The authors concluded that…
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Medical study · Medical research · 2021
Generation of human embryonic stem cell models to exploit the EWSR1-CREB fusion promiscuity as a common pathway of transformation in human tumors
…suppressor TP53. We expect the generation of isogenic lines carrying oncogenic fusions in various cell lineages to expand our general understanding of how those single genetic events drive tumorigenesis while providing valuable resources for drug discovery.