223 results for “Reaction Department”, page 10 of 12
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Court case · U.S. District Court, Southern District of Alabama · August 30, 2013 · in the opinion
Morgan v. Bill Vann Company, Inc. (2013)
…are not stricken (and motions to strike should not be filed in federal court) as a kneejerk reaction whenever a litigant is unhappy with either the contents of an exhibit or the other side's arguments…
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Medical study · Medical research · 1987
Immunocytological staining reactions of anti-carcinoembryonic antigen, Ca, and anti-human milk fat globule monoclonal antibodies on benign and malignant exfoliated mesothelial cells
This laboratory study tested whether three antibody stains could help tell mesothelioma apart from lung cancer and from benign conditions, using cells shed into body-cavity fluid (pleural or peritoneal effusions). The stains detected…
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Medical study · Medical research · 2016
New Markers for Separating Benign From Malignant Mesothelial Proliferations: Are We There Yet?
This was a literature review of laboratory tests for telling malignant mesothelioma from benign mesothelial reactions. The authors wrote that five older stains (GLUT-1, p53, IMP-3, epithelial membrane antigen and desmin) worked only in…
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Court case · Ohio Court of Appeals · September 4, 2014
Tucker v. CompuDyne Corp. (2014)
…paragraphs 18(a) and (b) of its inadvertently disclosed Litigation Analysis, modified to allow redaction of a few lines of counsel's legal impressions; plaintiffs largely won. An inadvertent disclosure of a privileged document can waive…
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Court case · New York Surrogate's Court · July 26, 2024
Matter of Lucano (2024)
…which caused mesothelioma and his death. The court said the requested redaction was really a request to seal court records, since the rules allow redaction only of limited confidential personal information. It held that sealing requires…
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Medical study · Medical research · 2019
Phase I study of YS110, a recombinant humanized monoclonal antibody to CD26, in Japanese patients with advanced malignant pleural mesothelioma
…toxicity. Corticosteroid, antihistamine, and acetaminophen administration before each infusion was adopted to limit infusion-related reactions (IRRs). Nine Japanese patients (seven men and two women, mean age of 62.2 years), three in each dosing cohort…
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Medical study · Medical research · 2020
A Phase II Study of Pazopanib in Patients with Malignant Pleural Mesothelioma: NCCTG N0623 (Alliance)
…had no earlier chemotherapy and 15 had received a pemetrexed-containing regimen. The main goal was the share alive and progression-free at 6 months without having stopped treatment for adverse reactions, refusal or other therapy…
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Medical study · Medical research · 2000
Serologic responses in patients with malignant mesothelioma: evidence for both public and private specificities
…protein. Antibodies to topoisomerase II beta were found in 13 of 14 patients and in 6 of 16 volunteers, though the volunteers' reactions were generally weak. Antibodies to U2AF(65) were found in two patients. Each…
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Medical study · Medical research · 2016
Utility of BAP1 Immunohistochemistry and p16 (CDKN2A) FISH in the Diagnosis of Malignant Mesothelioma in Effusion Cytology Specimens
…might also be useful in effusion cytology specimens, we examined 15 biopsies of epithelial mesotheliomas and 3 benign mesothelial reactions and corresponding effusion cytology paraffin-embedded cell blocks. Four cytology specimens were too scanty for p16…
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Medical study · Medical research · 2014
Randomized phase II trial of pemetrexed/cisplatin with or without CBP501 in patients with advanced malignant pleural mesothelioma
…in the two arms, aside from infusion reactions which occurred in 70% of patients treated with CBP501. While this randomized phase II trial met its primary endpoint of PFS at 4 months, other parameters such as…
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Medical study · Medical research · 2012
Safety and effectiveness of pemetrexed in patients with malignant pleural mesothelioma based on all-case drug-registry study
…asbestos exposure, and 8.3% had asbestosis as judged by the prescribing physician. Adverse drug reactions were reported in 84.2% of patients, and seven deaths (0.8%) were possibly associated with the chemotherapy. Interstitial lung…
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Medical study · Medical research · 2010
WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer
…lung cancer were vaccinated, and 10 could be evaluated for immune response. Seven of the 12 had mild (grade 1) injection-site reactions; no other side effects attributable to the vaccine were noted. Six of nine…
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Medical study · Medical research · 2014
Iron overload as a major targetable pathogenesis of asbestos-induced mesothelial carcinogenesis
…compared with about 600 days for crocidolite and amosite. Nitrilotriacetic acid, a chemical that promotes iron-driven reactions, significantly promoted tumor development for all three fibers. Homozygous deletion (complete loss) of the Cdkn2a/2b tumor-suppressor…
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Court case · New Jersey Superior Court, Appellate Division · April 20, 2016
Seymoure v. AO Smith Water Products Company (2016)
…s counsel planned to use the records in other litigation, and the order set no limit on that. The court remanded for a protective order requiring redaction and limiting use to this case unless employees consent.
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Court case · U.S. Court of Appeals, Third Circuit · March 21, 1996
Holbrook v. Lykes Bros. SS Co., Inc. (1996)
…since diagnosis and cause were the central issues. It upheld the admission of the defense radiation experts and the redaction of mesothelioma references in records. It found no unfair judicial conduct and refused a new judge…
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Medical study · Medical research · 2001
Localised spontaneous regression in mesothelioma -- possible immunological mechanism
…lobe. Blood samples from her last 11 months showed antibodies against mesothelioma. Two of these reactions faded and one stayed stable. The authors judged this strong circumstantial evidence linking the immune cells to the regression. They…
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Medical study · Medical research · 1978
Lymphocyte responses to phytohaemagglutinin in patients with asbestosis and pleural mesothelioma
…Two of the ten showed slight impairment, and all ten showed delayed skin reactions to common test substances. The authors concluded that the study suggests a link between impaired T-lymphocyte function and the scarring process…
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Medical study · Medical research · 1997
Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery
The purpose of this study was to determine the incidence and severity of thoracic reactions in patients undergoing intraperitoneal heated chemotherapy (IPHC). Forty-two patients who had intraperitoneal disseminated malignancies were treated with cytoreductive surgery (CS…
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Medical study · Medical research · 2019
Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia
…and acidity provide microenvironment for selection under evolutionary pressure and proliferation in cancer cells. Carbonic anhydrases (CAs) are a superfamily of metalloenzymes present in all life kingdoms, equilibrating the reactions among CO2, bicarbonate and H+. CA9…
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Medical study · Medical research · 2019
Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: Toward the era of mesothelioma prevention
…caused by modern industrial development. The major pathogenic mechanisms include oxidative stress either via catalytic reactions against the asbestos surface or frustrated phagocytosis of macrophages, and specific adsorption of hemoglobin and histones by asbestos fibers in…