1,074 results for “Reaction Department”, page 13 of 54
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Medical study · Medical research · 2010
Potassium octatitanate fibers (TISMO) induce pleural mesothelial cell reactions with iron accumulation in female A/J mice
…to assess responses. Only the fiber-shaped TISMO, morphologically similar to asbestos, induced a severe reaction of the pleura. A number of TISMO fibers were observed in the alveoli, indicating penetration through the pleura. Following Berlin…
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Medical study · Medical research · 1985
Malignant mesothelioma and CEA staining
…which is neither tumor- nor organ-specific. The author added that CEA staining results are not valid unless this reaction is first removed by absorbing the antisera with NCA. Earlier reports describing CEA in mesothelioma had…
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Medical study · Medical research · 1986
Gallium scanning in differentiating malignant from benign asbestos-related pleural disease
…no history of exposure. Scans were also positive in 3 of the 16 patients with benign disease (19%), and tissue removed from these three showed a strong inflammatory reaction. Among asbestos-exposed patients, the scan's…
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Medical study · Medical research · 1977
Immune adherence reactivity of rat alveolar macrophages following inhalation of crocidolite asbestos
…a statistically significant difference. Sheep red cells, which cannot take part in this reaction, stuck far less to macrophages from exposed rats. Treating the cells with antiserum against the complement component C3 reduced adherence to 4…
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Medical study · Medical research · 2013
Diffuse intrapulmonary malignant mesothelioma masquerading as interstitial lung disease: a distinctive variant of mesothelioma
…micropapillary, and solid patterns. Initial diagnoses by referring pathologists included reactive changes (1), hypersensitivity pneumonitis versus drug reaction (1), desquamative interstitial pneumonia versus neoplasm (1), and mesothelioma (2). Microscopic pleural involvement was identified in 4 cases…
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Medical study · Medical research · 2012
New roads open up for implementing immunotherapy in mesothelioma
…were seen. Another was their own group's dendritic-cell vaccine trial, which was well tolerated and induced an immune reaction. They also described mouse experiments with drugs such as celecoxib and zoledronic acid. The authors…
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Medical study · Medical research · 1974
Antemortem diagnosis in two cases of malignant peritoneal mesothelioma
…the abdomen. A biopsy taken by peritoneoscopy, a scope inserted into the abdomen, was read as consistent with mesothelioma or an inflammatory reaction. The Armed Forces Institute of Pathology then confirmed mesothelioma. He died, and autopsy…
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Medical study · Medical research · 2021
Mesothelin-targeted CAR-T cell therapy for solid tumors
…15. In the first trial in humans, one mesothelioma patient had a severe allergic reaction (anaphylaxis). A Memorial Sloan Kettering conference abstract reported results for 19 pleural mesothelioma patients given the cells into the chest. Of…
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Medical study · Medical research · 1994
Highly specific spectrophotometric method for palladium(II) determination with 3-(5'-tetrazolylazo)-2,6-Diaminotoluene in the presence of chlorides. Kinetic and equilibrium study of reactions
…Equilibrium constants beta(nl) for reactions PdCl(2-)(4) + nH(3)L(2+) right harpoon over left harpoonright harpoon over left harpoon PdCl(4-n) (H(2)L)(2n-2)(n) + n Cl(-) + n H(+) were…
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Medical study · Medical research · 2002
Analysis of the biological and chemical reactivity of zeolite-based aluminosilicate fibers and particulates
…NR8383). Our objective was to quantitatively determine the biological response upon interaction of the test particulates/fibers with lung macrophages and to evaluate the efficacy of surface iron on the zeolites to promote the Fenton reaction…
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Medical study · Medical research · 1985
Pathologic changes in the small airways of the guinea pig after amosite asbestos exposure
… where these fibers penetrated the airway walls, an interstitial inflammatory and fibrotic reaction (asbestosis) occurred. It is concluded that 1) amosite asbestos produces diffuse abnormalities throughout the noncartilagenous airways and possibly the cartilagenous airways as well…
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Medical study · Medical research · 1993
Activation of UICC crocidolite: the effect of conversion of some ferric ions to ferrous ions
…The amount of iron in asbestos fibers, its oxidation state, and its availability to specific chelating agents determine their ability to catalyze the aforementioned reactions. In the present study, the activation of UICC crocidolite was achieved…
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Medical study · Medical research · 2003
Asbestos bodies: clues to the mechanism of asbestos toxicity?
…lung, ascorbate was oxidized to oxalate in the presence of H2O2, a reaction inhibited by the iron chelator deferoxamine. The author called this a novel mechanism that may contribute to the pathogenicity of asbestos fibers. Oxidation…
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Medical study · Medical research · 1996
Distinctive profile of alveolar macrophage-derived cytokine release induced by fibrogenic and nonfibrogenic mineral dusts
…BAL) for BAL cell populations and cytokine production in conjunction with histopathological assessment of lung tissue. Chrysotile B and short 4T30 chrysotile fibers induced chronic inflammatory reactions characterized by alveolar macrophage (AM) accumulation that resulted, respectively…
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Medical study · Medical research · 2002
Palliative physicians persuade procurators fiscal
… a post-mortem was likely. The visit was delayed a day, but she had a complicated grief reaction. The case led to talks with local clinicians and officials. Police officers then stopped interviewing relatives for identification…
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Medical study · Medical research · 2013
Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy
…at 8 weeks. The most common severe side effects were fatigue (15%), a hand-foot skin reaction called palmar-plantar erythrodysesthesia (13%) and rash (9%). Eleven patients (21%) stopped treatment because of side effects. PET scan…
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Medical study · Medical research · 2002
Gemcitabine-induced erysipeloid skin lesions in a patient with malignant mesothelioma
…gemcitabine-induced erysipeloid skin reaction was reported in a small number of patients with previous history of radiotherapy or lymphedema. We reported a male patient who developed erysipeloid skin reaction following gemcitabine treatment in the absence…
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Medical study · Medical research · 1992
Immunohistochemical study of 158 lung carcinomas
…carcinomas. The marker CEA stained only 33% of small cell and 60% of large cell carcinomas, and eight (26%) poorly differentiated squamous cell carcinomas showed no reaction. EMA stained about 90% of all four tumour groups…
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Medical study · Medical research · 1981
The biological effects of mineral fibres
…In the studies reviewed, glass fibres injected into animals' body cavities produced mesotheliomas, while inhaled glass fibre produced little tissue reaction. Studies of glass fibre workers had so far been negative. The review also described reports…
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Medical study · Medical research · 2002
Early inflammatory response to asbestos exposure in rat and hamster lungs: role of inducible nitric oxide synthase
…inducible nitric oxide synthase (iNOS) plays a role in the development of asbestos-related pulmonary disorders. The pulmonary reactions of rats and hamsters upon exposure to asbestos fibers are well known to be disparate. In addition…