1,074 results for “Reaction Department”, page 16 of 54
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Medical study · Medical research · 2016
A regional approach for CAR T-cell therapy for mesothelioma: from mouse models to clinical trial
…at 196 days. In an earlier intravenous Phase I trial that included three MPM patients, all three developed antibodies and one had an anaphylactic reaction. The authors described their ongoing Phase I trial (NCT02414269), which gives…
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Medical study · Medical research · 2020
Reactive mesothelial hyperplasia mimicking mesothelioma in an African green monkey (Chlorocebus aethiops)
…records showed no history of radiation. The authors concluded that this was a benign reactive mesothelial hyperplasia, a reaction to inflammation of the body linings (polyserositis), that mimicked an epithelioid mesothelioma. They stated that the cause…
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Medical study · Medical research · 2016
Immune responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells stimulated with particulate silica
…and NLR-C12, and the genes ASC and caspase-1 were significantly increased at certain time points. The authors concluded that NLR-C12 may be a candidate inflammasome sensor in the reaction triggered by particulate silica.
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Medical study · Medical research · 1983
Small-airway lesions in patients exposed to nonasbestos mineral dusts
…which they call mineral dust airways disease, is a nonspecific reaction of the small airways to inorganic particulates. The presence of such changes casts considerable doubt on the theory that small-airway abnormalities in asbestos workers…
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Medical study · Medical research · 1987
Paraplegia due to massive asbestos-related pleural and mediastinal fibrosis
…damage was triggered by reduced blood flow in an already severely compromised circulation. They said they felt the tissue findings represented an unusually florid immune reaction to asbestos. In their view this resembled idiopathic mediastinal fibrosis.
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Medical study · Medical research · 2010
Collagen accumulation over time in the murine lung after exposure to crocidolite asbestos or Libby amphibole
…which the authors said would be unexpected so soon. The authors concluded that LA's fibrotic reaction did not reach crocidolite's level in the same period. They noted that the mouse model may imperfectly represent…
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Medical study · Medical research · 1974
Lymphohematogenous spread of asbestos
…kidney, brain and other organs, and of what damage they cause. The author concluded that knowing the injury reaction and tissue dose-response would help determine how much asbestos, and what kind, if any, humans can…
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Medical study · Medical research · 1984
Quantitative x ray microanalysis of pulmonary mineral particles in a patient with pneumoconiosis and two primary lung tumours
…fire clay mineral. The authors concluded the method reliably identified individual particles. They noted it cannot show whether the dust caused the tissue reaction, and that the particles analysed probably did not represent all minerals present.
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Medical study · Medical research · 1979
Milky spots (Taches laiteuses) as structures which trap asbestos in mesothelial layers and their significance in the pathogenesis of mesothelial neoplasia
…were seen in either group. The authors concluded that milky spots may trap blood-borne particles. They suggested that the cells' reaction to trapped fibres might be an early step toward tumours of the body cavities.
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Medical study · Medical research · 2001
Cutaneous toxicity after intradermal vaccination with Mycobacterium vaccae against lung cancer and malignant mesothelioma
This letter reported two patients at the Royal Marsden Hospital who developed unusual skin reactions after injections into the skin of SRL172, a heat-killed Mycobacterium vaccae vaccine being tested against cancer. The first, a 52…
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Medical study · Medical research · 2013
Melan A (A103) is not a marker of mesothelioma
…supplier (Lab Vision). The authors concluded that melan A (A103) is not expressed in mesotheliomas and that the earlier positive results most likely reflected a false-positive reaction of that antibody. The study did not examine…
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Medical study · Medical research · 2003
Regression of AK7 malignant mesothelioma established in immunocompetent mice following intratumoral gene transfer of interferon gamma
…10% with a control virus. The authors concluded that local interferon gamma had antitumor activity in this model. They noted that the immune reaction was not enough to produce an efficient memory response, since tumors relapsed.
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Medical study · Medical research · 1987
Response of mouse lung to crocidolite asbestos. 2. Pulmonary fibrosis after long fibres
…These findings suggest that injury to bronchial and bronchiolar epithelium allows long fibres to reach the interstitium where subsequent macrophage-fibroblast interactions result in a severe fibrotic reaction that resembles the bronchiolar component of human asbestosis.
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Medical study · Medical research · 2010
Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung
…lungs and the elevation of proinflammatory cytokines in the plasma (Leptin and IL-6 at 6h) confirmed the induction of an inflammatory reaction. This inflammatory reaction was accompanied by a decrease in the local oxidative stress…
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Medical study · Medical research · 2017
Malignant peritoneal mesothelioma and Crohn disease
Mesothelial reaction simulating peritoneal diffuse malignant mesothelioma (MM) has been reported in the setting of Crohn ileitis. To our knowledge, peritoneal MM arising in patients with inflammatory bowel disease (IBD) has not been reported. The purpose…
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Medical study · Medical research · 1974
Response of cell cultures to asbestos fibers
The reaction of macrophages to asbestos and glass fibers was studied by light and by electron microscopy. Measurements were made of LDH release, staining with erythrosine B, and lactate production. Size and shape of asbestos fibers…
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Medical study · Medical research · 2013
Sources of organic nitrogen at the serpentinite-hosted Lost City hydrothermal field
The reaction of ultramafic rocks with water during serpentinization at moderate temperatures results in alkaline fluids with high concentrations of reduced chemical compounds such as hydrogen and methane. Such environments provide unique habitats for microbial communities…
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Medical study · Medical research · 2009
The thermal transformation of Man Made Vitreous Fibers (MMVF) and safe recycling as secondary raw materials (SRM)
…wt.% of the melts of Rock and Glass wool gave promising results in terms of viscous sintering reactions and resistance to staining with the only weak characteristic being the color properties of the fired bodies which…
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Medical study · Medical research · 2012
Unusual DNA mismatch repair-deficient tumors in Lynch syndrome: a report of new cases and review of the literature
Immunohistochemical detection of DNA mismatch repair proteins and polymerase chain reaction detection of microsatellite instability have enhanced the recognition of mismatch repair-deficient neoplasms in patients with Lynch syndrome and, consequently, led to the identification of…
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Medical study · Medical research · 2016
ACR Appropriateness Criteria Review ACR Appropriateness Criteria® Occupational Lung Diseases
Occupational lung disease is a category of disease entities characterized by a reaction of the lung parenchyma to inhaled aerosolized particles found in the environment. This document summarizes the imaging appropriateness data for silicosis, coal worker…