558 results for “Reaction Department”, page 16 of 28
-
Medical study · Medical research · 1983
Interactions of chrysotile asbestos with erythrocyte membranes
…cells and bind to cell membranes which may become wrapped around the fibers. This reaction is prevented by pretreatment of the cells with neuraminidase. The distribution of lectins which bind to membrane glycoproteins is altered by…
-
Medical study · Medical research · 2008
Characteristics and modifying factors of asbestos-induced oxidative DNA damage
…Natural iron chelators, such as citrate, adenosine 5'-triphosphate and guanosine 5'-triphosphate, did not inhibit this reaction. Second, we used time-lapse video microscopy to evaluate how cells cope with asbestos fibers. RAW264.7 cells…
-
Medical study · Medical research · 2013
Differential expression of extracellular matrix constituents and cell adhesion molecules between malignant pleural mesothelioma and mesothelial hyperplasia
…carcinogenesis. We analyzed a panel of 84 genes involved in extracellular matrix remodeling and cell adhesion by polymerase chain reaction (PCR) array in 15 samples of epithelioid mesothelioma and 10 samples of reactive mesothelial hyperplasia (MH…
-
Medical study · Medical research · 2003
Comparative study of antioxidant properties and cytoprotective activity of flavonoids
…studied in a model photochemical system. Rate constants of the second order reaction obtained by competitive kinetics suggested flavonoids to be more effective scavengers of oxygen anion-radicals than ascorbic acid. By competitive replacement all flavonoids…
-
Medical study · Medical research · 2002
Chemiluminescent detection of induced reactive oxygen metabolite production of human polymorphonuclear leucocytes by anthophyllite asbestos
…tyrosine kinase, which resides in the pathway to cause PMN activation. The strong ROM reaction of PMN by anthophyllite suggests that the surface characteristics of the fiber may participate in the pathogenic mechanisms of anthophyllite asbestos.
-
Medical study · Medical research · 2009
Asbestos health hazard: a spectroscopic study of synthetic geoinspired Fe-doped chrysotile
…the Fe doping extent. Geoinspired synthetic chrysotile at different Fe doping extents has been obtained as unique phase by hydrothermal reaction in the presence or not of metallic Fe in the synthetic environment. The results highlight…
-
Medical study · Medical research · 1999
Expression of genes coding for proteoglycans and Wilms' tumour susceptibility gene 1 (WT1) by variously differentiated benign human mesothelial cells
…to WT1, PGs and hyaluronan synthase, we studied their expression by semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR) analyses. The expressions of these genes were all associated with a variation in phenotypic differentiation. Cell lines…
-
Medical study · Medical research · 1983
Exposure to asbestos: psychological responses of mesothelioma patients
…to evaluate asbestos exposure, acquisition of increased risk information, and retrospective reporting of cognitive and behavioral reactions (particularly smoking behavior) to risk information. Twenty-eight patients (74%) had direct occupational contact with asbestos, and six patients…
-
Medical study · Medical research · 2014
ERC/mesothelin is expressed in human gastric cancer tissues and cell lines
…MKN-7, MKN-74, NUGC-3, NUGC-4 and TMK-1) using reverse transcription-polymerase chain reaction, flow cytometry, immunohistochemistry and immunoblotting. We also examined the N-ERC/mesothelin concentrations in the supernatants of cultured cells…
-
Medical study · Medical research · 1987
The stimulatory effects of asbestos on NADPH-dependent lipid peroxidation in rat liver microsomes
…It is not inhibited by superoxide dismutase, catalase and mannitol, indicating that oxygen radicals are not involved in the reaction. It is also not inhibited by desferrioxamine, indicating that it is not due to a release…
-
Medical study · Medical research · 2002
Black spots of the parietal pleura: morphology and formal pathogenesis
…in close correlation to lymphatic channels and blood vessels. Their formal pathogenesis is characterized by a mild fibrosis and an inflammatory reaction to the incorporated foreign particles. The proliferation of connective tissue may result in the…
-
Medical study · Medical research · 1983
Effect of intrabronchially instilled amosite on lavagable lung and pleural cells
…the study. No pleural reaction was seen in the saline instilled group. The inflammatory reactions indicated by the composition of the lavaged cells of the lung represent the in vivo toxicity of intrabronchially instilled amosite. The…
-
Medical study · Medical research · 2013
Overexpression of EPH receptor B2 in malignant mesothelioma correlates with oncogenic behavior
…we investigated EPHB2 in MM tumors compared with normal mesothelium. EPHB2 and downstream target expression were evaluated using reverse-transcriptase polymerase chain reaction and immunoblotting methods. The biological significance of EPHB2 in MM was evaluated using…
-
Medical study · Medical research · 2014
Morphological changes during enhanced carbonation of asbestos containing material and its comparison to magnesium silicate minerals
…mineral carbonation. The study revealed that oxalate even at a low concentration of 0.1M was effective in enhancing the extent of ACM carbonation and higher reaction temperatures also resulted in increased ACM carbonation. Formation of…
-
Medical study · Medical research · 2011
A₃ receptors are overexpressed in pleura from patients with mesothelioma and reduce cell growth via Akt/nuclear factor-κB pathway
…between adenosine and MM, the presence and functionality of ARs were explored in human healthy mesothelial cells (HMC) and in malignant mesothelioma cells (MMC). ARs were analyzed by using reverse transcriptase-polymerase chain reaction, Western blotting…
-
Medical study · Medical research · 2015
Poorly differentiated neoplasms of unknown primary site: diagnostic usefulness of a molecular cancer classifier assay
…PDNs without a definitive lineage diagnosed by histology or IHC (median 18 stains, range 9-46). Biopsies from these 30 patients had MCCA (92-gene reverse transcriptase-polymerase chain reaction mRNA) performed. Additional IHC, gene sequencing…
-
Medical study · Medical research · 2010
No implication of Simian virus 40 in pathogenesis of malignant pleural mesothelioma in Slovenia
…antibody against Simian virus 40 (Pab280). SV40-expressing Wi-38 cells were used as positive control in both PCR and immunohistochemistry. In real-time polymerase chain reaction analyses, only 4 samples gave products with primer pairs…
-
Medical study · Medical research · 1996
Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus
…of this tumor suppressor gene in the development of these hereditary rat tumors. By using reverse transcriptase (RT)-polymerase chain reaction (PCR) analysis, the sequence of the rat VHL gene was determined over the portion of…
-
Medical study · Medical research · 2014
Tumors that mimic asbestos-related mesothelioma: time to consider a genetics-based tumor registry?
…Some of these metastatic malignancies, particularly carcinomas and sarcomas of the pleura, pericardium and peritoneum, may undergo desmoplastic reaction in the pleura, thereby mimicking mesothelioma, rather than the primary tumor. Encasement of the lung by direct…
-
Medical study · Medical research · 2009
Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
…Moreover, BC and BCM were able to increase (.)OH formation from H(2)O(2) in the Fenton reaction (determined by electron spin resonance spectroscopy). Addition of Vit A and RA to lung epithelial cells that…