442 results for “General Electric”, page 18 of 23
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Medical study · Medical research · 2018
Multimodality treatment of malignant pleural mesothelioma
…radical approaches such as EPP and hemithoracic RT post-EPP are less effective than was previously assumed. In general, there are still a great number of unanswered questions and unknown factors regarding the ideal treatment approach…
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Medical study · Medical research · 2015
Epithelioid pleural mesothelioma concurrently associated with miliary pulmonary metastases and minimal change nephrotic syndrome - A hitherto undescribed case
…nodules appeared on chest CT. Transbronchial biopsy specimen of the nodules showed the metastatic MPM in the lung. The patient died because of the worsening of the general condition. To our knowledge, this is the first…
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Medical study · Medical research · 2019
Localized multiple malignant epithelioid peritoneal mesotheliomas arising from the hepatoduodenal ligament and diaphragm: a case report
…diaphragmatic resection were performed. The final pathological diagnosis was multiple malignant epithelioid mesotheliomas. Our patient has had no recurrence for 20 months postoperatively. In general, malignant peritoneal mesotheliomas are classified as diffuse tumors, which are often…
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Medical study · Medical research · 2018
Integrated Histogenetic Analysis Reveals BAP1-Mutated Epithelioid Mesothelioma in a Patient With Cancer of Unknown Primary
…Additionally, this case highlights typical features of BAP1 TPDS with its general susceptibility to cancers, with pleural and peritoneal mesotheliomas as most prevalent clinical entities and the typically more benign course of these epithelioid mesotheliomas compared…
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Medical study · Medical research · 2019
Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register
…in the epidemiological studies. In general it should be recommended that a positive history of exposure to asbestos or to asbestos-containing materials are at risk for the development of a MMTVT and should be monitored.
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Medical study · Medical research · 1981
Asbestos--can it be used safely?
…to crocidolite. For Quebec chrysotile miners and millers, the mesothelioma risk was perhaps three to six times that of the general population, compared with 100-200 times in insulation workers exposed to mixed fibres. Some data…
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Medical study · Medical research · 2015
Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma
…H28 cells), pRB1 (H28 cells) and E2F1 and TYMS activity (except H226 cells) were also evident. E2F1 knockdown decreased cell viability more significantly than TYMS knockdown. In general, thymidine kinase 1, ribonucleotide reductase M1, c-myc…
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Medical study · Medical research · 2016
Consensus Report of the 2015 Weinman International Conference on Mesothelioma
…as high mobility group box 1 and fibulin-3, are promising. There was general agreement that current treatment for MM, which is based on surgery and standard chemotherapy, has a modest effect on the overall survival…
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Medical study · Medical research · 2004
The doctors and the dockers
…The Registrar General's occupational mortality report for 1951, noted excess tumors of the lung and stomach for dockers. Elevated Standardized Mortality Ratios for lung cancer had consistently been calculated by the Registrar General for the…
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Medical study · Medical research · 2004
Mortality in a cohort of vermiculite miners exposed to fibrous amphibole in Libby, Montana
…a 14% increase in mortality for mine workers exposed occupationally to 100 f/ml.y or about 3.2% for a general population exposed for 50 years to an ambient concentration of 0.1 f/ml…
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Medical study · Medical research · 2013
Domestic asbestos exposure: a review of epidemiologic and exposure data
…low-level chrysotile-exposed workers. Lung burden studies (n = 6) were also evaluated as a surrogate of exposure. In general, available results for domestic exposures are lower than the workers' exposures. Recent simulations of low…
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Medical study · Medical research · 1997
Pulmonary carcinogenicity of inhaled particles and the maximum tolerated dose
…end of a subchronic study. However, there is no general agreement about quantification of these end points to define the MTD. To determine whether pulmonary responses are indicative of the MTD, we suggest defining an MTD…
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Medical study · Medical research · 2012
Lung cancer incidence in Canadian petroleum workers
…cancer incidence, although exposures to the single agents studied did not emerge as strong predictors of lung cancer incidence. Maintenance work may be a surrogate for general exposures to several agents (eg, polycyclic aromatic hydrocarbons, metals…
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Medical study · Medical research · 2014
Changes of mesothelin and osteopontin levels over time in formerly asbestos-exposed power industry workers
…deciding between intensive clinical work-up and continued surveillance appeared inadequate for the evaluated markers. While general conclusions cannot be drawn, we can say that the results of the two patients would be consistent with a…
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Medical study · Medical research · 1979
Pleural plaques and neoplasia in Finland
…The authors suggested that slight asbestos exposure causes plaques while heavy exposure leads to plaques and lung fibrosis. They considered the results in accord with the general view of the association between plaques and asbestos exposure.
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Medical study · Medical research · 2008
Feasibility of a screening programme for lung cancer in former asbestos workers
…Incidence rate was 149 per 10(5), equal to that in the male general population of similar age. The expenses for diagnosis were 1014 and 244962 Euro per screened subject and screen-detected lung cancer case…
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Medical study · Medical research · 2001
Educational differences in lung cancer mortality in male smokers
…This excess mortality was about 40% of the similar excess observed in the general population of men of similar age. Educational differences in lung cancer mortality in the total Finnish population are likely to be mainly…
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Medical study · Medical research · 1992
Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resistant to amosite toxicity: a possible mechanism for tumor promotion by asbestos
…cells that were only immortalized by SV40. The sensitivity of normal mesothelial cells to asbestos does not appear to be simply a result of general fragility of the mesothelial cells, since similar levels of hydrogen peroxide…
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Medical study · Medical research · 2002
The combination of effects on lung cancer of cigarette smoking and exposure in quebec chrysotile miners and millers
…equivalent to exposure amounting to 700 million particles per cubic foot x years. The refutation of the multiplicative hypothesis in these data reinforces its inapplicability in general; but the additive hypothesis is not generally applicable either…
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Medical study · Medical research · 2015
Extended follow-up of lung cancer and non-malignant respiratory disease mortality among California diatomaceous earth workers
…significant. Associations were attenuated when adjusted for smoking and asbestos exposure. Mortality from NMRD was significantly increased over the entire follow-up compared to the general population (SMR=1.37, 95% CI 1.17 to 1.60)…