558 results for “Reaction Department”, page 18 of 28
-
Medical study · Medical research · 1999
Low dose cabergoline induced interstitial pneumonitis
…a "hypersensitivity-like" interstitial lung disease, which cleared almost completely within 2 months after simple drug withdrawal. Circumstantial evidence suggests a so far undescribed adverse lung reaction to cabergoline, devoid of the more usual pleural changes.
-
Medical study · Medical research · 1990
Reactive lesions of the pleura. Immunohistochemical characterization
…The antibodies Leu M1, HEA 125 and BMA 130c (against CEA) showed no reaction in subserosal and mesothelial cells. With the antibody HMFG 2, however, a weak reaction could be observed. A distinction between reactive and…
-
Medical study · Medical research · 1983
Keratin proteins and carcinoembryonic antigen in lung carcinoma: an immunoperoxidase study of fifty-four cases, with ultrastructural correlations
…all squamous cell carcinomas. This reaction was particularly helpful in identifying squamous differentiation in poorly differentiated areas and in cases in which tonofilaments appeared to be sparse or absent on electron microscopy. Weak focal staining for…
-
Medical study · Medical research · 2002
E-cadherin, E-selectin and vascular cell adhesion molecule: immunohistochemical markers for differentiation between mesothelioma and metastatic pulmonary adenocarcinoma?
…staining patterns for VCAM and E-selectin, there were significant differences in the expression of E-cadherin: while nearly all adenocarcinomas stained positively, there was almost no staining reaction of the mesotheliomas. Therefore, E-cadherin -- in…
-
Medical study · Medical research · 2001
Sorption of nonpolar aromatic contaminants by chlorosilane surface modified natural minerals
…headgroups and chemical properties. Silanol groups of the diatomite and zeolite were modified by chemical reaction with the chlorosilanes resulting in a stable covalent attachment of the organosilanes to the mineral surface. The alteration of surface…
-
Medical study · Medical research · 1982
Malignant mesothelioma of the tunica vaginalis testis: report of first case with preoperative diagnosis
…and the second with documented history of exposure to asbestos. The identity of the tumor was confirmed by a positive immunoperoxidase reaction directed against mesothelial cells. A review of the previously described ten cases is presented…
-
Medical study · Medical research · 1974
Correlation between the tissue response and asbestos fiber content
…and here secondary factors may be concerned. Electron microscopy suggests that optically visible fibers constitute a reasonably constant proportion of the total irrespective of the pathological reaction. Light microscopy may thus afford a guide to the…
-
Medical study · Medical research · 2014
Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma
…lines. Copy number analysis was measured by quantitative polymerase chain reaction and fluorescence in situ hybridization. Copy number analysis revealed copy number gains (CNGs) in chromosomal region 8q24 in six of 12 MPM cell lines. MicroRNA…
-
Medical study · Medical research · 1999
Kaposi's sarcoma following malignant mesothelioma
…of mesothelioma diagnosis and preceded the onset of Kaposi' sarcoma with a time lapse of 13 months. HHV8 DNA was detected by polymerase chain reaction in lesional Kaposi's sarcoma but not within mesothelioma. By immunostaining…
-
Medical study · Medical research · 1998
Modulation of mitochondrial gene expression in pulmonary epithelial cells exposed to oxidants
…RNA was extracted, reverse transcribed, and amplified by polymerase chain reaction with degenerate primers to visualize alterations in gene expression. The seven clones obtained were sequenced and encoded the mitochondrial genes, NADH dehydrogenase subunits ND5 and…
-
Medical study · Medical research · 2003
Oxalate deposition on asbestos bodies
…vitro generated approximately 42 nmol of oxalate in 24 hours. Oxalate generation was diminished significantly by the inclusion of either deferoxamine or dimethylthiourea in the reaction mixture. Incubation of asbestos bodies and uncoated fibers isolated from…
-
Medical study · Medical research · 2001
Can semi-automated image cytometry on induced sputum become a screening tool for lung cancer? Evaluation of quantitative semi-automated sputum cytometry on radon- and uranium-exposed workers
…workers resected for lung cancer, and 200 controls (50% smokers), were stained using the Papanicolaou (Pap) method and the Feulgen reaction with thionin. Cytometry was performed using the Cyto-Savant automated system. Atypical nuclei were found…
-
Medical study · Medical research · 2000
Crocidolite induces cell transformation and p53 gene mutation in BALB/c-3T3 cells
…foci and subjected to mutational analysis. Eleven exons of the p53 gene from eight transformed cell lines were analyzed for alterations using polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP). Alterations were found in seven…
-
Medical study · Medical research · 1983
Ventilatory failure due to asbestos pleurisy
…because of extension of the pleural fibrosis into the lung. Two of these patients had pleural uptake of 67-gallium citrate attributable to the inflammatory reaction. With the increasing duration since onset of exposure in the…
-
Medical study · Medical research · 1973
Experimental infective pneumoconiosis: effect of asbestos dust and Candida albicans infection on the lungs of rhesus monkeys
…albicans infection alone caused acute inflammatory reaction in the early stages while at the termination of experiment (330 days) the only evidence of pulmonary candidiasis was a few small fibrotic foci of compactly arranged reticulin fibers…
-
Medical study · Medical research · 1994
An experimental approach to the evaluation of the biopersistence of respirable synthetic fibers and minerals
…initial evaluation of solubility and durability, they cannot simulate the dynamics of inhalation deposition and clearance and the subsequent systemic reaction to fibers and minerals that occurs in the animal. To evaluate the biopersistence of synthetic…
-
Medical study · Medical research · 1983
Effect of asbestos on the metabolism of vasoactive substances in isolated perfused guinea pig lungs
…The tissue response consisted of both inflammatory reaction of terminal and respiratory bronchioles and diffuse alveolar septal infiltration with interstitial fibrosis. The reaction was characterized at six months by a progressive bronchiolitis obliterans with fibroblastic proliferation…
-
Medical study · Medical research · 1986
The in vitro activities of a highly carcinogenic mineral fibre--potassium octatitanate
…free radicals via a catalytic reaction requiring the presence of transition elements which are either not present or only present at low concentrations in erionite or Fybex. This type of reaction may not be related to…
-
Medical study · Medical research · 2013
miR-1 induces growth arrest and apoptosis in malignant mesothelioma
…comparators. To confirm microarray data, we used real-time quantitative polymerase chain reaction. Representative cell lines H513 and H2052 were used in functional analyses of miR-1. In addition to several novel MPM-associated microRNAs, we…
-
Medical study · Medical research · 2011
Epidermal growth factor receptor overexpression in malignant pleural mesothelioma: prognostic correlations
…status. Results were correlated with clinico-pathological characteristics and long-term survival. Thirty-eight cases (46%) demonstrated a positive IHC reaction [30/57 (52%) epithelial and 8/20 (40%) biphasic whereas sarcomatous MPM were negative]. No…