84 results for “Reaction Department”, page 4 of 5
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Medical study · Medical research · 1993
Pathogenesis of mesothelial reactions to asbestos fibers. Monocyte recruitment and macrophage activation
Exposure to asbestos fibers leads to a variety of mesothelial reactions: pleural effusions, fibrotic pleural plaques, and malignant mesotheliomas. An animal model was developed to reproduce these lesions in C57B1/6 mice using weekly intraperitoneal injections…
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Medical study · Medical research · 1985
Characterization of the bronchoalveolar cellular response in experimental asbestosis. Different reactions depending on the fibrogenic potential
This was an animal experiment in male Wistar rats. Each rat received a single injection into the windpipe of saline (control), 5 mg of UICC chrysotile B asbestos, or 5 mg of very short 4T30 chrysotile fibers. Lung washings (bronchoalveolar lavage)…
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Medical study · Medical research · 1977
Immunological studies of patients with asbestosis. I. Studies of cell-mediated immunity
…Cape crocidolite and amosite. On skin tests, reactions to tuberculin did not differ significantly between the groups. Five of 26 patients and no controls failed to react to Candida extract. Fourteen of 26 patients and 6…
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Medical study · Medical research · 2004
Asbestos and the pleura: a review
…in pleural disease, laboratory research on how asbestos damages cells, and United States public policy. They described four benign pleural reactions (effusions, circumscribed plaques, diffuse pleural thickening and rounded atelectasis) as well as mesothelioma. Citing other…
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Medical study · Medical research · 1992
The role of free radicals in asbestos-induced diseases
…this reactive radical. However, asbestos also appears to catalyze electron transfer reactions that do not require iron. Iron chelators either inhibit or augment asbestos-catalyzed generation of the hydroxyl radical and/or pathological changes, depending on…
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Medical study · Medical research · 1980
Asbestosis and systemic lupus erythematosus
…as they knew, no such case had been described before. They suggested it could be a particular expression of immune reactions reported in many asbestos workers, possibly analogous to Caplan-Collinet syndrome (silicosis with rheumatoid arthritis).
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Medical study · Medical research · 1981
Asbestos inhalation and the induction of splenic lymphocytic proliferation in the rat
…The authors concluded that asbestos inhalation produced two distinct effects on the macrophages, one attributed to a putative asbestos-related neoantigen. They suggested immune reactions might contribute to asbestosis. The number of rats was not reported.
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Medical study · Medical research · 1988
Effects of informing workers of their health risks from exposure to toxic materials
…definitely should be told. The authors concluded that informing workers carried little risk of mental distress, and suggested that information alone was not sufficient to change smoking behavior. The study could not assess short-term reactions.
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Medical study · Medical research · 1986
Cytokine regulation of lung fibroblast proliferation. Pulmonary and systemic changes in asbestos-induced pulmonary fibrosis
…later loss of the blood-cell inhibitor may be a consequence or amplifier of fibrosis. They noted that, given the injection method, their data do not relate to very early reactions to low-level inhaled asbestos.
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Medical study · Medical research · 1978
Lymphocyte responses to phytohaemagglutinin in patients with asbestosis and pleural mesothelioma
…Two of the ten showed slight impairment, and all ten showed delayed skin reactions to common test substances. The authors concluded that the study suggests a link between impaired T-lymphocyte function and the scarring process…
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Medical study · Medical research · 1980
The follow-up study of skin reactivity to recall antigens and E- and EAC-RFC profiles in blood in asbestos workers
We have determined cutaneous DTH reactions to SK-SD and PPD and peripheral blood lymphocyte profiles in a group of asbestos workers in two consecutive surveys. It was found that asbestosis and, to a lesser extent…
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Medical study · Medical research · 1994
The human evidence: parenchymal and pleural changes
Asbestos inhalation can cause fibrotic reactions both in the lung parenchyma and in the pleura. The incidence and relative proportions of these lesions in any cohort will be dependent on: (1) the time factor: both asbestosis…
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Medical study · Medical research · 1991
Radiological features of asbestos-related visceral pleural changes
…Generally, visceral pleural reactions follow the mesothelial cells response to various injurious substances, including asbestos, and even saline. The changes are nonspecific. They may occur subsequent to pleural reactions associated with many conditions, which include tuberculosis…
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Medical study · Medical research · 1983
Biochemical components of bronchoalveolar lavage in early experimental asbestosis of the sheep: phospholipase A2 activity, prostaglandin E2 and proteins
…significantly increased in both low and high dose groups. These changes in protein and lipid components of BAL following asbestos exposure constitute early indices of lung inflammatory reactions which may contribute to the development of asbestosis.
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Medical study · Medical research · 2010
Analysis on the co-localization of asbestos bodies and Fas or CD163 expression in asbestos lung tissue by in-air micro-pixe
…Ferrous iron, and Magnesium (the components of asbestos) deposition. These results indicate that the system could be useful for investigating the pathogenesis of inhaled particle-induced immune reactions and for determining harmful levels of exogenous agents.
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Medical study · Medical research · 1972
A histochemical study of the asbestos body coating
…after iron extraction were tested by histochemical methods for mucopolysaccharides. The results of the reactions suggest that acid mucopolysaccharides are present in the coating of most bodies. During the formation of the bodies acid mucopolysaccharides might…
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Medical study · Medical research · 2016
Synchrotron X-ray microscopy reveals early calcium and iron interaction with crocidolite fibers in the lung of exposed mice
…inhaled asbestos fibers; (2) the extent of the deposition of these ions is proportionally directly related and (3) iron and calcium deposition on inhaled asbestos fibers is concomitant with the appearance of inflammatory and hyperplastic reactions.
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Medical study · Medical research · 1990
Asbestos and other toxins
…most significant factors in behavioral stability and coping. The author concluded that telling exposed workers the truth about their health appeared to reinforce their usual patterns of behavior rather than create new or non-adaptive reactions.
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Court case · Pennsylvania Superior Court · August 25, 2005 · in the opinion
Summers v. Certainteed Corp. (2005)
…asbestos related ailments, including lung cancer, excessive cigarette smoking, heart disease, asthma, emphysema and allergic reactions. Mr. Summers has three of those conditions — excessive cigarette smoking, asthma, emphysema (a cause of chronic obstructive lung disease). ¶ 22…
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Court case · Pennsylvania Superior Court · March 22, 2000 · in the opinion
Lonasco v. A-Best Products Co. (2000)
…obesity, asthma, emphysema and allergic reactions. All three appellant-husbands smoked cigarettes at some point in their lives and the record reflects that appellant Watkins is overweight and suffers from heart problems. Taylor, 666 A.2d…