985 results for “General Electric”, page 48 of 50
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Medical study · Medical research · 1994
Spirometric impairments in long-term insulators. Relationships to duration of exposure, smoking, and radiographic abnormalities
…and reduced FEV1/FVC are both more frequent in insulators who have smoked (compared with NS insulators or smokers in the general population) suggests an interaction between asbestos and smoking in producing both these physiologic abnormalities.
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Medical study · Medical research · 2010
Defining asbestos: differences between the built and natural environments
…occurring in its natural setting in El Dorado Hills, California led to an increased concern of the potential for low-level environmental exposure to asbestos to the general public. The current dilemma we find ourselves in…
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Medical study · Medical research · 2001
Educational differences in lung cancer mortality in male smokers
…This excess mortality was about 40% of the similar excess observed in the general population of men of similar age. Educational differences in lung cancer mortality in the total Finnish population are likely to be mainly…
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Medical study · Medical research · 1992
Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resistant to amosite toxicity: a possible mechanism for tumor promotion by asbestos
…cells that were only immortalized by SV40. The sensitivity of normal mesothelial cells to asbestos does not appear to be simply a result of general fragility of the mesothelial cells, since similar levels of hydrogen peroxide…
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Medical study · Medical research · 2002
The combination of effects on lung cancer of cigarette smoking and exposure in quebec chrysotile miners and millers
…equivalent to exposure amounting to 700 million particles per cubic foot x years. The refutation of the multiplicative hypothesis in these data reinforces its inapplicability in general; but the additive hypothesis is not generally applicable either…
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Medical study · Medical research · 2015
Extended follow-up of lung cancer and non-malignant respiratory disease mortality among California diatomaceous earth workers
…significant. Associations were attenuated when adjusted for smoking and asbestos exposure. Mortality from NMRD was significantly increased over the entire follow-up compared to the general population (SMR=1.37, 95% CI 1.17 to 1.60)…
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Medical study · Medical research · 2011
Iron as a target of chemoprevention for longevity in humans
…Alzheimer's disease. Furthermore, a recent epidemiological study reported that iron reduction by phlebotomy was associated with decreased cancer risks in a general population. Given that the required amounts of iron decrease during ageing, the fine…
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Medical study · Medical research · 1992
Three types of human lung tumour cell lines can be distinguished according to surface expression of endogenous urokinase and their capacity to bind exogenous urokinase
…u-PA. Large cell carcinoma cell lines expressed high amounts of u-PA and bound large amounts of u-PA. In general, expression of u-PA and u-PA binding was enhanced after PMA treatment. (ii…
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Medical study · Medical research · 2010
Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus
…derived signals, which vanished after tumor eradication. These data indicate that transcriptional targeting of viral replication by the Mdk promoter represents a promising general strategy for oncolytic virotherapy of cancers with up-regulated Mdk expression, including…
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Medical study · Medical research · 2010
Paratesticular mesothelioma. Report of a case with comprehensive review of literature
…or secondary tumors also need to be considered. A clinicopathologic evaluation of a case of tunical diffuse mesothelioma in a 74-year-old male from the AMR Series is the starting point for this general review.
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Medical study · Medical research · 2015
Adsorption of bovine serum albumin onto synthetic Fe-doped geomimetic chrysotile
…pyrolysis-gas chromatography), changed when the BSA was adsorbed on the nanofibres. In general, results suggested that minute amount (less than 1 wt%) of Fe doping in chrysotile affected the protein-nanofibre interactions, supporting the role…
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Medical study · Medical research · 1965
The occurrence of pleural calcification among asbestos insulation workers
…the pleura was found to be immune. The diagnostic importance of such unilateral calcification is stressed since even unilateral calcification is uncommon in the general population and when it occurs, a traumatic or infectious history can…
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Medical study · Medical research · 1988
Multistage modelling of lung cancer mortality in asbestos textile workers
…suggest whether a carcinogen appears to act at an early, intermediate or late stage, and the general statistical methods applied here will retain their usefulness as further models are developed and larger data sets become available.
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Medical study · Medical research · 1995
Proportionate mortality among construction laborers
…of time within the union, were younger, and first entered the union after 1955. This is the first study that has examined the general mortality experience limited to construction laborers only (Bureau of Census code 869).
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Medical study · Medical research · 1993
Asbestos exposure among Finnish lung cancer patients: occupational history and fiber concentration in lung tissue
…construction jobs, and valuable information about the exposure levels could be obtained by the mineral fiber analyses. In general, there was a good accord between the exposure categorization and the fiber burden measured in the lung.
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Medical study · Medical research · 1999
Modulation of genotoxic and related effects by carotenoids and vitamin A in experimental models: mechanistic issues
…In spite of some discrepant data, the general trend was that both carotenoids and vitamin A are poorly effective in acting as nucleophiles, nor do they appear to substantially interfere with the induction or repair of…
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Medical study · Medical research · 2013
Potential toxicity and safety evaluation of nanomaterials for the respiratory system and lung cancer
…regarding chronic exposure at low doses is more complicated. The long-term accumulation of ENPs in the respiratory system cannot be excluded. However, at present, exposure data for the general public regarding ENPs are not available.
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Medical study · Medical research · 1991
Cell toxicity, hemolytic action and clastogenic activity of asbestos and its substitutes
…grade of crystallinity and/or fiber size. These effects of calcium silicates and some clay minerals were generally low but varied with mineral species. In general, the cell toxicity, hemolytic and clastogenic activities of the asbestos…
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Medical study · Medical research · 1997
Asbestos, Simian virus 40 and malignant mesothelioma
…confirmation but raised the possibility that SV40 is an important cofactor. If about 5% of the general population and 60% of patients with mesothelioma carried the virus, this would suggest an approximately 30-fold increased risk…
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Medical study · Medical research · 2020
Heterologous sarcomatoid pleural mesothelioma with osteosarcomatous differentiation: a report of autopsy case that accomplished trimodality therapy and review of the literature
This was a case report with a review of published cases. It described a 69-year-old man in Japan, a demolition worker for 40 years, with heavy asbestos exposure. Biopsied lung held 35,523 asbestos bodies per gram of dry lung. Tests showed…