558 results for “Reaction Department”, page 6 of 28
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Medical study · Medical research · 2002
Palliative physicians persuade procurators fiscal
… a post-mortem was likely. The visit was delayed a day, but she had a complicated grief reaction. The case led to talks with local clinicians and officials. Police officers then stopped interviewing relatives for identification…
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Medical study · Medical research · 2013
Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy
…at 8 weeks. The most common severe side effects were fatigue (15%), a hand-foot skin reaction called palmar-plantar erythrodysesthesia (13%) and rash (9%). Eleven patients (21%) stopped treatment because of side effects. PET scan…
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Medical study · Medical research · 2002
Gemcitabine-induced erysipeloid skin lesions in a patient with malignant mesothelioma
…gemcitabine-induced erysipeloid skin reaction was reported in a small number of patients with previous history of radiotherapy or lymphedema. We reported a male patient who developed erysipeloid skin reaction following gemcitabine treatment in the absence…
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Medical study · Medical research · 1992
Immunohistochemical study of 158 lung carcinomas
…carcinomas. The marker CEA stained only 33% of small cell and 60% of large cell carcinomas, and eight (26%) poorly differentiated squamous cell carcinomas showed no reaction. EMA stained about 90% of all four tumour groups…
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Medical study · Medical research · 1981
The biological effects of mineral fibres
…In the studies reviewed, glass fibres injected into animals' body cavities produced mesotheliomas, while inhaled glass fibre produced little tissue reaction. Studies of glass fibre workers had so far been negative. The review also described reports…
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Medical study · Medical research · 2002
Early inflammatory response to asbestos exposure in rat and hamster lungs: role of inducible nitric oxide synthase
…inducible nitric oxide synthase (iNOS) plays a role in the development of asbestos-related pulmonary disorders. The pulmonary reactions of rats and hamsters upon exposure to asbestos fibers are well known to be disparate. In addition…
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Medical study · Medical research · 1971
Induction of interferon in human subjects by poly I:C
…responsive again after a 10-day period. The authors could not define this refractory period precisely. Fever was the only consistent clinical reaction. Serum was tested from 19 patients, and none showed complement-fixing antibodies against…
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Medical study · Medical research · 1983
Lipid peroxidation in microsomes induced by crocidolite fibres
…produced a concomitant induction in microsomal lipid peroxidation. This increase was very rapid as the reaction was almost complete within 10 min. The ability of these fibres to induce this process after a short period of…
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Medical study · Medical research · 2001
Study of inflammatory responses to crocidolite and basalt wool in the rat lung
…dehydrogenase (LDH) activity were determined in the bronchoalveolar lavage (BAL). Both types of fibers induced a prolonged inflammatory reaction in the lung. All the parameters studied in the experimental groups were more markedly elevated after 3…
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Medical study · Medical research · 1987
Enhanced lipid peroxidation and lysosomal enzyme activity in the lungs of rats with prolonged pulmonary deposition of crocidolite asbestos
…for example 75.87 versus 30.81 mg at three months), and microscopy showed granulomas containing fibres. The fibrotic reaction tended to diminish by seven months. Activity of two lysosomal enzymes, beta-glucuronidase and cathepsin D…
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Medical study · Medical research · 1987
Cytogenetic findings in an effusion secondary from pleural mesothelioma
…years earlier a similar episode had been diagnosed as tuberculous pleuritis. Routine examination of cells in the fluid showed only a nonspecific reaction of the lining cells, and a pleural biopsy found no signs of cancer…
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Medical study · Medical research · 1982
A study of macrophage-mediated initiation of fibrosis by asbestos and silica using a diffusion chamber technique
…the chamber) from the target tissue. Fibrous reactions surrounding the chambers were quantitated by macroscopic and histological scoring, and by measurement of 14C glycine incorporated at the reaction site. Using this model the fibrogenicity of Rhodesian…
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Medical study · Medical research · 2006
Biocatalytic ammonolysis of (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl)-5-ethyl ester: preparation of an intermediate to the dipeptidyl peptidase IV inhibitor Saxagliptin
…temperatures, and amounts of enzyme and ammonium carbamate. Adding calcium chloride raised the amide yield to 79%. Placing Ascarite above the reaction mixture, where it was presumed to absorb carbon dioxide, raised the yield to 95%…
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Medical study · Medical research · 1984
Pulmonary toxicology of silica, coal and asbestos
…the air sacs and fibrotic nodules failed to develop. The author argued that the simple lung lesion of coal workers is best seen as a nonspecific reaction to heavy dust accumulation. In red-blood-cell tests…
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Medical study · Medical research · 1993
Bidirectional modulation of TNF-alpha production by alveolar macrophages in asbestos-induced pulmonary fibrosis
…alpha mRNA in AMs. These data indicate that lower levels of TNF-alpha resulted from inhibition at the gene expression level and provide evidence for bidirectional modulation of TNF-alpha production by AMs during inflammatory reactions.
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Medical study · Medical research · 1927
Histology of Pulmonary Asbestosis
…inside scavenger cells, and in scarred and caseous areas. They gave a Prussian-blue colour reaction in a chemical test. Zoologists judged them not animal, and the general opinion of botanical and chemical experts was that…
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Medical study · Medical research · 2004
Re: Controlled use of asbestos
…which were not published, reported fibrotic lesions or lung damage; in 1966 the Coalinga sample produced the most severe reaction. The authors stated that UCC consultants misrepresented Pinkerton's data. Their review of King City mine…
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Medical study · Medical research · 1965
Asbestos and neoplasia: diffuse mesothelial tumors. Criteria for diagnosis of diffuse mesothelial tumors
…periodic acid-Schiff reaction was nearly always negative. A colleague found hyaluronidase-removable acid mucopolysaccharide in all 17 mesotheliomas examined and in none of 20 adenocarcinomas. However, the author had seen an identical reaction in pleural…
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Medical study · Medical research · 2011
Role of oxidants in interstitial lung diseases: pneumoconioses, constrictive bronchiolitis, and chronic tropical pulmonary eosinophilia
…among other materials; and tropical pulmonary eosinophilia, caused by an immune reaction to filarial parasites. The review described earlier studies in which lung-wash (bronchoalveolar lavage) cells from patients with coal workers' pneumoconiosis, asbestosis and silicosis…
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Medical study · Medical research · 1989
Reactions of asbestos-exposed workers to notification and screening
…In this study, we assessed reactions of asbestos-exposed workers to a letter notifying them of their risk for asbestos-related illnesses and the availability of a medical screening program. Two hundred forty-seven workers who…