223 results for “Reaction Department”, page 7 of 12
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Medical study · Medical research · 2014
Correlation between TS, MTHFR, and ERCC1 gene polymorphisms and the efficacy of platinum in combination with pemetrexed first-line chemotherapy in mesothelioma patients
…combination with pemetrexed or pemetrexed monotherapy were enrolled. Genomic DNA was isolated from peripheral blood. Using polymerase chain reaction and high resolution melt methods, the variable number of tandem repeat, the G>C single nucleotide polymorphism (SNP…
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Medical study · Medical research · 1987
Congenital polycystic tumor of the atrioventricular node (endodermal heterotopia, mesothelioma): a histogenetic appraisal with evidence for its endodermal origin
…similar distribution to that of the argyrophil cells. A positive reaction of different distribution from that of the argyrophil cells was noted in a varying number of tubule-lining cells for carcinoembryonic antigen, epithelial membrane antigen…
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Medical study · Medical research · 2012
Increased circulating miR-625-3p: a potential biomarker for patients with malignant pleural mesothelioma
…healthy controls. miRNAs with significantly different abundance between cases and controls were validated in a larger series of MM patients and in an independent series of MM patients using quantitative real-time polymerase chain reaction. Levels…
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Medical study · Medical research · 1990
Reactive lesions of the pleura. Immunohistochemical characterization
…The antibodies Leu M1, HEA 125 and BMA 130c (against CEA) showed no reaction in subserosal and mesothelial cells. With the antibody HMFG 2, however, a weak reaction could be observed. A distinction between reactive and…
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Medical study · Medical research · 2002
E-cadherin, E-selectin and vascular cell adhesion molecule: immunohistochemical markers for differentiation between mesothelioma and metastatic pulmonary adenocarcinoma?
…staining patterns for VCAM and E-selectin, there were significant differences in the expression of E-cadherin: while nearly all adenocarcinomas stained positively, there was almost no staining reaction of the mesotheliomas. Therefore, E-cadherin -- in…
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Medical study · Medical research · 1982
Malignant mesothelioma of the tunica vaginalis testis: report of first case with preoperative diagnosis
…and the second with documented history of exposure to asbestos. The identity of the tumor was confirmed by a positive immunoperoxidase reaction directed against mesothelial cells. A review of the previously described ten cases is presented…
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Medical study · Medical research · 2014
Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma
…lines. Copy number analysis was measured by quantitative polymerase chain reaction and fluorescence in situ hybridization. Copy number analysis revealed copy number gains (CNGs) in chromosomal region 8q24 in six of 12 MPM cell lines. MicroRNA…
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Medical study · Medical research · 1999
Kaposi's sarcoma following malignant mesothelioma
…of mesothelioma diagnosis and preceded the onset of Kaposi' sarcoma with a time lapse of 13 months. HHV8 DNA was detected by polymerase chain reaction in lesional Kaposi's sarcoma but not within mesothelioma. By immunostaining…
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Medical study · Medical research · 2013
miR-1 induces growth arrest and apoptosis in malignant mesothelioma
…comparators. To confirm microarray data, we used real-time quantitative polymerase chain reaction. Representative cell lines H513 and H2052 were used in functional analyses of miR-1. In addition to several novel MPM-associated microRNAs, we…
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Medical study · Medical research · 2011
Epidermal growth factor receptor overexpression in malignant pleural mesothelioma: prognostic correlations
…status. Results were correlated with clinico-pathological characteristics and long-term survival. Thirty-eight cases (46%) demonstrated a positive IHC reaction [30/57 (52%) epithelial and 8/20 (40%) biphasic whereas sarcomatous MPM were negative]. No…
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Medical study · Medical research · 2010
Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma
…We also analyzed WIF-1 and SFRPs promoter methylations in 46 mesothelioma tissues, 8 mesothelioma cell lines by methylation-specific polymerase chain reaction (MSP). WIF-1 promoter methylation was observed in 34 of 46 mesothelioma tissues…
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Court case · Maryland Court of Special Appeals · May 31, 2006 · in the opinion
John Crane, Inc. v. Puller (2006)
…929] husband's personality or ability to engage in all the intangible associations which marriage brings; he too suffers the effect of the change, if only in reaction to his wife's unhappiness. Today, at least…
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Court case · Texas Court of Appeals · December 29, 1988 · in the opinion
Pecorino v. Raymark Industries, Inc. (1988)
…pleaded that the Defendants' breach of these various duties (as well as the fact that these products precipitated great harm which was not a consequence of any unique or unforeseeable reaction of the user) caused Mr…
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Medical study · Medical research · 2019
Proton Beam Therapy and Immune Checkpoint Inhibitors in Malignant Pleural Mesothelioma
…and a biopsy showed alveolar injury. Corticosteroids led to rapid symptom resolution. The authors hypothesized that proton therapy caused immune "priming" and a later "recall" reaction. They concluded that the combination, particularly with very large treatment…
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Medical study · Medical research · 2023
The role of single nucleotide polymorphisms related to iron homeostasis in mesothelioma susceptibility after asbestos exposure: a genetic study on autoptic samples
…healthy Italian individuals contained in the 1000 genomes database were considered for comparison. PCR-multiplex amplification followed by SNaPshot mini-sequencing reaction was used. The findings presented in this study show that the allelic and genotypic…
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Medical study · Medical research · 2017
Three-dimensional finite-element based deformable image registration for evaluation of pleural cavity irradiation during photodynamic therapy
…The method used is appropriate for analyzing problems over complicated domains, such as when the domain changes (as in a solid-state reaction with a moving boundary), when the desired precision varies over the entire domain…
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Medical study · Medical research · 2010
Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma
…PI3KCA mutations/amplifications or PTEN inactivation were observed. Real-time polymerase chain reaction revealed the decreased expression of TSC1 c-DNA in half of the tumours. In vitro cytotoxicity studies showed the STO cell line to…
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Medical study · Medical research · 2009
Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat
…fibers have been suggested. We previously reported that multiwall carbon nanotubes (MWCNT) induced lung inflammation, granulomas and fibrotic reactions. The same MWCNT also caused mutations in epithelial cells in vitro and in vivo. These inflammatory and…
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Medical study · Medical research · 2000
Mesothelial proliferations. An increasing morphologic spectrum
…electron microscopy, fluorescence in situ hybridization, polymerase chain reaction and cytogenetics, and stated that testing should be tailored to the tumor's appearance. They argued that separating mesothelioma from its mimics generally did not change treatment…
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Medical study · Medical research · 2000
HBME-1, MOC-31, WT1 and calretinin: an assessment of recently described markers for mesothelioma and adenocarcinoma
… all reactive pleuras were negative. The reaction with Leu-M1 was graded as equivocal in 25% of the adenocarcinomas. All 24 of the autopsy cases of mesothelioma were negative for WT1 and in many operative specimens…