23 results for “General Electric”, page 1 of 2
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Medical study · Medical research · 1998
Asbestos lung burden and asbestosis after occupational and environmental exposure in an asbestos cement manufacturing area: a necropsy study
This necropsy (autopsy) study examined lung tissue from the consecutive autopsies done at the General Hospital of Casale Monferrato, Italy, home to a large asbestos cement factory, from July 1985 to July 1988. Of 55 autopsies…
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Medical study · Medical research · 2020
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma
…Therefore, 7 of 155 apparently unrelated mesothelioma patients carried BLM+/- mutations, significantly higher (P = 6.7E-10) than the expected frequency in a general, unrelated population from the gnomAD database, and 2 of 7 carried…
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Medical study · Medical research · 1991
Malignant mesothelioma after exposure to asbestos in dental practice
…found 0.7 x 10^6 crocidolite fibres per gram of dry lung. The authors described this as lower than expected with longstanding occupational exposure but higher than in the general population. No chrysotile fibres were found…
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Medical study · Medical research · 1984
Fiber size and number in amphibole asbestos-induced mesothelioma
…of crocidolite fibers, 0.2 X 10(6)/g; these values represent an approximately 250-fold increase over those found in the general population. Crocidolite fibers were significantly narrower than amosite fibers (mean width, 0.13…
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Medical study · Medical research · 2011
Mesothelioma in an individual following exposure to crocidolite-containing gaskets as a teenager
…per gram of deparaffinized (wax-removed) wet tissue. Two of the authors' laboratories use 20 or fewer per gram of wet tissue as the general-population level. Electron microscopy at 15,000 times magnification detected only…
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Medical study · Medical research · 1993
Malignant mesothelioma after environmental exposure to blue asbestos
…or as employees of CSR or ABA, the cohort was 4890 (2187 men, 2703 women). Residents were exposed through general contamination from milling, mill tailings used on roads, yards and playgrounds, and household contact with workers…
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Medical study · Medical research · 1997
Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos
…hour in that medium, so the authors suggested it was released from the cells continuously. They found no sign of general membrane damage. Activity of the enzyme gamma glutamylcysteine synthetase fell by 47%, while four other…
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Medical study · Medical research · 1993
The production of TNF-alpha and IL-1-like activity by bronchoalveolar leucocytes after intratracheal instillation of crocidolite asbestos
…both substances. The authors noted that low-level endotoxin in culture media could have contributed to background release. They concluded that, in general, asbestos exposure increased production of both substances, with short-term variations after instillation.
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Medical study · Medical research · 2007
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines
…The authors noted that cell experiments cannot precisely reflect conditions in the body, and that many changes probably reflect general responses to toxic substances. The authors concluded that the study identified several targets for further investigation…
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Medical study · Medical research · 2020
Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat
Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80-90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos…
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Medical study · Medical research · 1996
Asbestos exposure and ovarian fiber burden
Epidemiologic studies suggest increased risk of epithelial ovarian cancer in female asbestos workers and increased risk of malignancy in general in household contacts of asbestos workers. Ovaries were studied from 13 women with household contact with…
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Medical study · Medical research · 2007
Genotoxic mechanisms of asbestos fibers: role of extranuclear targets
…fibers are carcinogenic to both humans and experimental animals. The continued discoveries of exposure routes whereby the general public is exposed to asbestos suggest a long-term, low-dose exposure for a large number of people…
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Medical study · Medical research · 2016
Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden
We have conducted a population-based study of pleural mesothelioma patients with occupational histories and measured asbestos lung burdens in occupationally exposed workers and in the general population. The relationship between lung burden and risk, particularly…
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Medical study · Medical research · 2020
The Wittenoom legacy
…products in Western Australia. As a result, the state has recorded a higher malignant-mesothelioma mortality rate than in any other Australian state and in any defined general population in the world. Thus, the legacy of…
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Medical study · Medical research · 2021
In vitro toxicity of fibrous glaucophane
…blueschist rocks of California (USA) currently mined for construction purposes. Dust generated by the excavation activities might potentially expose workers and the general public. The aim of this study was to determine whether fibrous glaucophane induces…
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Medical study · Medical research · 1980
Electron microscopy applied to studies of the biological significance of defects in crocidolite asbestos
…planar faults, and pores. Fibres sectioned in lung tissue and fibres taken from in vitro exposure to blood serum show evidence of erosion by two mechanisms--preferential attack at (100) planar defects and general surface dissolution.
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Medical study · Medical research · 1987
Some biological properties of respirable iron ore dust
…found in age-matched control animals. While there was a significant increase of the incidence of tumors in general in WAG inbred rats up to 2 years following dust exposure, this did not persist into old…
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Medical study · Medical research · 1982
Fiber counting and analysis in the diagnosis of asbestos-related disease
…large numbers. Numbers of asbestos bodies markedly underestimate total numbers of fibers present in lung. In patients from the general population, the mean number of asbestos fibers is about 1 X 10(6)/g dry lung;…
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Medical study · Medical research · 1990
Cancer mortality and exposure to crocidolite
…a further 800 f/ml shorter than 5 µm. Samples from the general area outside the plant showed up to 2 f/ml longer than 5 µm. Rogers noted that de Klerk et al had applied…
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Medical study · Medical research · 2002
The quantitative risks of mesothelioma and lung cancer in relation to asbestos exposure: the Wittenoom data
…and mill. It covered 12 shifts and collected 38 static samples, and it was reported only in general terms in 1968. Others had derived median estimates of 50 fibres/ml for ever mill workers, 12 fibres…