9 results for “Owens-Illinois”
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Medical study · Medical research · 2006
Saving the asbestos industry, 1960 to 2006
…million in sponsorship by 1999. Citing documents from a Texas court case, the article reported that Owens-Illinois made regular payments to Wagner from 1986, probably exceeding $300,000 in total. During this period Wagner's…
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Medical study · Medical research · 2017
Loss of BRCA1-associated protein 1 (BAP1) expression is rare in non-small cell lung cancer
This laboratory study, by Vancouver pathologists, asked how often non-small cell lung cancer (NSCLC) loses a protein called BAP1. Loss of BAP1 on tissue staining helps pathologists diagnose malignant mesothelioma, so the authors wanted to know how…
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Medical study · Medical research · 1951
Carcinoma and asbestosis of the lung; report of a case
This article reports a single case. The patient, a 39-year-old man, had been a ship's steward for five years and before that had kept a greengrocery business for fifteen years. Twenty years earlier he had worked for twelve months in an asbestos…
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Medical study · Medical research · 1964
Diffuse mesothelioma and exposure to asbestos dust in the Merseyside area
This 1964 report described 17 people with diffuse mesothelioma (16 pleural, one peritoneal) in Merseyside, England. Most cases came from Liverpool cancer and thoracic surgery records for 1955 to 1963. The author re-examined tissue, took work…
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Medical study · Medical research · 1971
Asbestos exposure to coke oven operators
…not necessarily with benzpyrene. They offered another explanation. Coke ovens and gas retorts require effective insulation, much of it containing asbestos, and the authors had been informed that its repair and maintenance were often the responsibility…
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Medical study · Medical research · 2019
Refining classification of malignant pleural mesothelioma reveals its Achilles' heel
…gene-activity results were checked against protein levels in a replication series. The author concluded that the present classification cannot predict the most effective treatments and that the study opens a window for new targeted treatments.
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Medical study · Medical research · 2020
A new trajectory approach for investigating the association between an environmental or occupational exposure over lifetime and the risk of chronic disease: Application to smoking, asbestos, and lung cancer
…dose and the timing of exposure. The proposed approach opens new perspectives for the analyses of dose-time-response relationships between protracted exposures and the risk of developing a chronic disease, by providing a complete picture…
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Medical study · Medical research · 2019
Pemetrexed-loaded nanoparticles targeted to malignant pleural mesothelioma cells: an in vitro study
…is more effective than Pe alone in inhibiting MPM cell line malignant phenotype. The innovative use of specifically targeted GNPs opens the perspective of local intrapleural administration to avoid normal cell toxicity and enhance chemotherapy efficacy.
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Medical study · Medical research · 2018
Tumor-specific genetic variants can be detected in circulating cell-free DNA of malignant pleural mesothelioma patients
…time the presence of ctDNA within circulating DNA of treatment naïve MPM patients. This finding opens perspectives towards the use of ctDNA as a biomarker for (early and differential) diagnosis, treatment and treatment monitoring of MPM…